When a nobleman is threatened by a family curse on his newly inherited estate, detective Sherlock Holmes is hired to investigate.
Baggage handlers Bud and Lou accidentally stumble upon Frankenstein's Monster, Dracula and the Wolf Man.
Frankenstein's unscrupulous colleague, Dr. Bohmer, plans to transplant Ygor's brain so he can rule the world using the monster's body, but the plan goes sour when he turns malevolent and goes on a rampage.
Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.
Grave robbers open the grave of the wolf man and awaken him. He doesn't like the idea of being immortal and killing people when the moon is full so tries to find Dr. Frankenstein, in the hopes that the doctor can cure him. Dr. Frankenstein has died; however, his monster is found.
One of the sons of late Dr. Henry Frankenstein finds his father's ghoulish creation in a coma and revives him, only to find out the monster is controlled by Ygor who is bent on revenge.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
Deranged scientist, Gustav Niemann, escapes from prison and overtakes the director of a traveling chamber of horrors, soon reviving the infamous Count Dracula, the frozen Frankenstein Monster, and the Wolf Man.
A deformed tormented girl drowns herself after her lover is framed for murder and guillotined. Baron Frankenstein, experimenting with the transfer of souls, places the boy's soul into her body, bringing Christina back to life. Driven by revenge, she carries out a violent retribution on those responsible for both deaths.
Mad Dr Frankenstein recruits an evil dwarf, a Neanderthal man, and others to help him put a brain in the body of a brute.
After the death of Victor Frankenstein, two figures vie for control of his monster and the radical technology that created him: the scientist's daughter, and an immortal wizard assisted by a blind bird-woman with an unquenchable thirst for blood.
The baron's grandson rents the family castle to a TV crew to fund his atomic revival of the family monster.
Victor Frankenstein's search for the secret of life leads to the creation of a monster that consumes his life and family.
Dr. Frankenstein and her assistant, Dr. Yanco, are going to bring one of their experiments to life in Santo Vs. Frankenstein's Daughter. She intends to use a monster named Ursus to do her evil bidding. Using a youth serum to retain their vitality, the doctors set their sights upon none other than El Santo. They need his super human blood to regenerate a stronger youth serum. They kidnap Santo's goddaughter, Norma and lure him into Dr. Frankenstein's lab where he is captured and enslaved. Will Santo make it out alive?
Professor Frankenstein creates a teenager from an accident victim, who gets angry when he learns he is going to be taken apart.
Frankenstein, a young medical student, trying to create the perfect human being, instead creates a misshapen monster. Made ill by what he has done, Frankenstein is comforted by his fiancée; but on his wedding night he is visited by the monster.
Tampering with life and death, Henry Frankenstein pieces together salvaged body parts to bring a human monster to life; the mad scientist's dreams are shattered by his creation's violent rage as the monster awakens to a world in which he is unwelcome.
Teenagers Scott and Mary are on their way to a Halloween party when their car breaks down, and they encounter a creepy castle where the depraved Dr. Frankenstein seeks to put Scott's brain in his monstrous creation. As for Mary, Count Dracula wants her for... well, you know.
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
Dr. Victor Frankenstein creates a monster to show his scientific theories, but soon leaves him. So the scientist tries to rebuild his life getting married with Janet, and retires to his castle with Igor. However the monster comes back to haunt Frankenstein, and so Victor finds out that the monster has ferocious sexual orientation to Janet. Frankenstein then calls the servant Igor to readjust the monster, but also Igor takes advantage of Janet...