Fidencio Borer, an apothecary in a village on the northern border of Mexico, discovers some old title of a mine in Arizona and decides to claim them. Trying to cross the border is a border guard intercepted by exaggerating in the line of duty. On the way is captured by a tribe of Apaches and is about to be burned alive, but thanks to the Great Head Horse Lying having toothache and learns that the prisoner it can heal, ordered his release on the condition that the cure. Fidencio would take the wheel and gets the eternal friendship of the Chief apache.
Bob Ford murders his best friend Jesse James in order to obtain a pardon that will free him to marry his girlfriend Cynthy. The guilt-stricken Ford soon finds himself greeted with derision and open mockery throughout town. He travels to Colorado to try his hand at prospecting in hopes that marriage with Cynthy is still in the cards.
Assaulted by outlaws, donkey-riding Rosie joins a silent drifter's search for gold in the Old West.
With the California Gold Rush beginning, Senator Frost's singing daughter Caroline loves a young army officer; the Senator can't stand him, and has him sent to California. Headstrong Caroline follows him by train, riverboat, and covered wagon, gaining companions en route: a vagrant Russian prince and gambler Johnny Lawlor, who just might take her mind off the army.
In this strange western version of Moby Dick, Wild Bill Hickok hunts a white buffalo he has seen in a dream. Hickok moves through a variety of uniquely authentic western locations - dim, filthy, makeshift taverns; freezing, slaughterhouse-like frontier towns and beautifully desolate high country - before improbably teaming up with a young Crazy Horse to pursue the creature.
Lucy, a young Victorian woman in the Old West, is being tormented by nightly visits from an incubus. Her friend Madeleine tries to console her, but is unable to help. A fallen woman, Lucy gets a job singing at the local saloon. However, the Incubus has followed her there; and things take an unexpected turn as Lucy and the Incubus, amidst the rowdy cowboys and saucy can-can girls, have their final showdown.
On the outskirts of town, the hard-nosed Vienna owns a saloon frequented by the undesirables of the region, including Dancin' Kid and his gang. Another patron of Vienna's establishment is Johnny Guitar, a former gunslinger and her lover. When a heist is pulled in town that results in a man's death, Emma Small, Vienna's rival, rallies the townsfolk to take revenge on Vienna's saloon – even without proof of her wrongdoing.
When John Mason's father is killed, John is wounded. Attracted to his nurse Alice, a conflict arises between him and his friend Ben who plans to marry Alice. John later finds the killer of his father but goes to face him not knowing Ben has removed the bullets from his gun.
Hoppy and his pals arrive in a remote town to investigate the counterfeiting of both U.S. and Mexican money; his only clues are the name "Mordigan" and a drawing of a comet. He quickly finds out that Mordigan is the town "boss"; but what or who is "the comet", and why are Mordigan and his henchmen intent on persecuting a young woman, her drunken brother, and her deathly ill sister-in-law who've also just arrived in town?
Saloon-bar singer Freddie gets very angry whenever boyfriend Blackie seems to be playing around. She always packs a six-shooter, so this is bad news for anything that happens to be in the way. As this is usually the local judge's rear-end, Freddie and friend Conchita are soon hiding out teaching school in the middle of nowhere.
A mute gunslinger fights in the defense of a group of outlaws and a vengeful young widow, against a group of ruthless bounty hunters.
A cowhand named Bob Blake visits with Sally Thompson and her kid-brother, Jimmy, on their hard-scrabble homestead adjoining the Steele Ranch where Bob works. He learns that their father just died, and he plans on seeing if he can make things a bit easier for them.
Legendary marshal Wyatt Earp, now a weary gunfighter, joins his brothers Morgan and Virgil to pursue their collective fortune in the thriving mining town of Tombstone. But Earp is forced to don a badge again and get help from his notorious pal Doc Holliday when a gang of renegade brigands and rustlers begins terrorizing the town.
A posse discovers a trio of men they suspect of murder and cow theft and are split between handing them over to the law or lynching them on the spot.
Bill Ramsbottom sells his English pub and drags his family off to Canada where he has inherited a ranch from his grandfather Wild Bill Ramsbottom. He ends up tangling with outlaw Black Jake, an Indian chief Blue Eagle, and the local law.
Three brothers stop off for a night in the town of Tombstone. The next morning they find one of their brothers dead and their cattle stolen. They decide to take revenge on the culprits.
Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.
Bret Maverick is a gambler who would rather con someone than fight them, and needs an additional $3k in order to enter a winner-takes-all poker game beginning in a few days. He joins forces with a woman with a marvelous Southern accent, and the two try and enter the game.
The simple story has the pair coming to the rescue of peace-loving Mormons when land-hungry Major Harriman sends his bullies to harass them into giving up their fertile valley. Trinity and Bambino manage to save the Mormons and send the bad guys packing with slapstick humor instead of excessive violence, saving the day.
An army gold shipment and its escort vanish in the Ozarks, prompting accusations of theft and desertion but frontiersman Old Shatterhand and Apache chief Winnetou help solve the mystery of the missing army gold.