Eccentric consulting detective Sherlock Holmes and Doctor John Watson battle to bring down a new nemesis and unravel a deadly plot that could destroy England.
Holmes and Dr. Watson tackle the case of a curse on the Baskerville bloodline in this ABC Movie of the Week adaptation.
Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider. Based on "The Sign of Four" and the short stories "The Dying Detective", "The Final Problem", "The Speckled Band" and "The Adventure of the Devil's Foot".
Dr. Watson, who served in the English armed forces and was in the Afghan war, retires and returns to his homeland, in England. Since the financial situation of the doctor is very precarious, his long-time friend Mr. Stamford offers him to rent a room in the house at 221-B Baker Street, which is rented by an elderly lady - Mrs. Hudson. The second rented room is already occupied by another gentleman - the mysterious Mr. Sherlock Holmes. Holmes makes an ambiguous impression on Watson. He conducts complex chemical experiments with blood, plays the violin, has the deepest knowledge about cigar ash, London dirt and criminal law, but at the same time demonstrates complete ignorance of well-known truths (for example, the fact that the Earth revolves around the Sun), does not read fiction, as well as books on history and philosophy. At the same time, very strange visitors constantly come to Holmes, and on the table he has portraits of personalities of a disgusting appearance.
Sherlock Holmes and Dr. Watson look into reports that a huge, vicious hound has killed Lord Charles Baskerville and that Lord Henry Baskerville is the next to be killed.
Holmes and Dr. Watson take on the case of a beautiful woman whose husband has vanished. The investigation proves strange indeed, involving six missing midgets, villainous monks, a Scottish castle, the Loch Ness monster, and covert naval experiments.
Having once again avoided criminal conviction, Professor Moriarity develops a murderous plan to “finish off” his last major nemesis, Sherlock Holmes, by making him fail to prevent the perfect crime. Does it involve a family curse, the crown jewels of England, or something else…
William James Moriarty, now known as the "Lord of Crime" to the public, and his allies are still working towards an ideal country by punishing the corrupt nobility. One day the government branch MI6, led by his brother Albert, is given the mission to eliminate a woman called Irene Adler for stealing confidential documents. In the meantime, Adler makes contact with Sherlock Holmes, who has become captivated by the mystery of the Lord of Crime.
Whitechapel, the slums of the East End in London, are being terrorized by a brutal serial killer called Jack the Ripper. While William James Moriarty receives a letter of request from his old teacher Jack Renfield, the Scotland Yard inspector Lestrade also seeks out Sherlock Holmes and John H. Watson for help in this matter.
William James Moriarty and Sherlock Holmes both become entangled with the ruthless "blackmailing king", Charles Augustus Milverton. Both determined to deal with him, Sherlock finally comes face to face with the mystery he's chased and longed for: the Lord of Crime.
At the end of the 19th century, the young mathematics professor William James Moriarty and his allies have decided to take on the British Empire in an effort to destroy the discriminatory class system and create an ideal country. During one of their missions to deliver punishment to the corrupt nobility, William meets a peculiar and intriguing consulting detective named Sherlock Holmes.
In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
England, at the start of World War Two. Mysterious wireless broadcasts, apparently from Nazi Germany are heard over the BBC. They warn of acts of terror in England, just before they take place. Baffled, the Defense Committee call in Sherlock Holmes.
A young woman turns to Holmes for protection when she's menaced by an escaped killer seeking missing treasure. However, when the woman is kidnapped, Holmes and Watson must penetrate the city's criminal underworld to find her.
The corpse of a shabbily dressed young woman has been discovered in the mud flats of the Thames at low tide. Police assume she's a prostitute, but Dr. Watson suspects something more and goes to his old friend Holmes, now retired and at very loose ends.
Two dubious characters disguise themselves as Holmes and Watson to gain attention and end up chasing counterfeiters and stolen stamps.
In 1947, long-retired and near the end of his life, Sherlock Holmes grapples with an unreliable memory and must rely on his housekeeper's son as he revisits the still-unsolved case that led to his retirement.
In London, a secret society led by lawyer Thaddeus Merrydew collects the assets of any of its deceased members and divides them among the remaining members. Society members start dropping like flies. Sherlock Holmes is approached by member James Murphy's widow, who is miffed at being left penniless by her husband. When Captain Pyke is shot, Holmes keys in on his mysterious Chinese widow as well as the shady Merrydew. Other members keep dying: Malcom Dearing first, then Mr. Baker. There is also an attempt on the life of young Eileen Forrester, who became a reluctant society member upon the death of her father. Holmes' uncanny observations and insights are put to the test.
Sherlock Holmes and Dr. Watson embark on a search for Cleopatra's ancient necklace, which has been stolen.
When Watson reads from the newspaper there have been two similar murders near Whitechapel in a few days, Sherlock Holmes' sharp deductive is immediately stimulated to start its merciless method of elimination after observation of every apparently meaningless detail. He guesses right the victims must be street whores, and doesn't need long to work his way trough a pawn shop, an aristocratic family's stately home, a hospital and of course the potential suspects and (even unknowing) witnesses who are the cast of the gradually unraveled story of the murderer and his motive.