In a small village of Communist-era Romania a young couple wish to marry, but Joseph Stalin dies the night prior to their wedding ceremony forcing the bride and groom to marry in silence.
Five college buddies from the University of Texas circa 1971 embark on a final road trip odyssey across the Mexican border before facing up to uncertain futures, in Vietnam and otherwise.
A young woman who has been in and out from rehab for the past 10 years returns home for the weekend for her sister's wedding.
Doreen is about to marry the man of her dreams, Hank, a mild-mannered guy who is equally as excited about marrying Doreen. However, Doreen's older brother, a wild man named Travis who's been estranged from her for several years, shows up to make amends, but instead he accidentally curses her. Doreen is now possessed by the devil. In Las Vegas is a homeless man known as Johnny Priest, who is the last known person to perform an exorcism in America. It's up to Travis and Hank to put aside their differences and travel from Chicago to Las Vegas to get Doreen an exorcism before it's too late and her soul is lost forever.
The story involves Arbuckle coming to the western town of Mad Dog Gulch after being thrown off a train and chased by Indians. He teams up with gambler/saloon owner Bill Bullhum, in trying to keep the evil Wild Bill Hickup away from Salvation Army girl, Salvation Sue. Fatty and Buster have a series of adventures trying to beat St. John, until they discover his one weakness: his ticklishness.