Two jobless Americans convince a prospector to travel to the mountains of Mexico with them in search of gold. But the hostile wilderness, local bandits, and greed all get in the way of their journey.
In the latter half of the 19th century, gold is discovered in the Black Hills, sacred land of the Lakota people. Gold diggers, profiteers and adventurers flock to the region. Among them is the hard-hearted land speculator Bludgeon, who tries to expel the Lakota using brutal methods. Lakota warriors retaliate, and soon the gold diggers' town becomes a battlefield.
During the California Gold Rush, two down-on-their-luck vaudevillians attempt to become wealthy by bringing a girlie show to an all-male western mining town.
Mitch Robbins' 40th birthday begins quite well until he returns home and finds his brother Glen, the black sheep of the family, in his sofa. Nevertheless he is about to have a wonderful birthday-night with his wife when he discovers a treasure map of Curly by chance. Together with Phil and unfortunately Glen he tries to find the hidden gold of Curly's father in the desert of Arizona.
Questions arise when Senator Stoddard (James Stewart) attends the funeral of a local man named Tom Doniphon (John Wayne) in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance (Lee Marvin). As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
Lash and Fuzzy sent to help John Watson with his stage line arrive to find him murdered. Recognizing the outlaws they trail them to their leader Baxter. But before Baxter can tell who the big boss is he is shot. After getting the stage through to assure the mail contract, Lash now realizes who the boss is.
In order to make Tug Cardwell (William Phipps) sign over his rich gold claim to them, John Avery (Robert Shayne), Gypsy Avery (Veda Ann Borg) and Jackson (Marshall Reed) hire Bob Rankin (Douglas Fowley') to kidnap Tug's sweetheart Jane Whipple (Elaine Riley). Rankin hides Jane and then demands half the mine from the other crooks. Dave Saunders (Tim Holt) and Chito Rafferty (Richard Martin), friends of Tug's, find Jane and taker her to safety. The conspirators then shoot Rankin, capture Tug and force him to take them to his claim. Dave and Chito are close behind.
The coming of the railroad to Cedar City spells the end of the stagecoach as the government gives the mail contract to the fastest means of delivery. McCord loses the stagecoach line gambling with the new buyer, but has enough hidden money to buy a ranch and some cattle. To make more money, he starts a gang to rob the railroad, express offices and steal cattle. But the railroads send out special agent Cameron to end his reign of violence.
Sgt. Renfrew and Constable Kelly go aloft to search for a plane missing with a shipment of gold from the Yukon Mine Company. Inventor Speavy has devised a power ray which disrupts electrical impulses, and Morgan and his gang of crooks has brought in Prof. Lewis to increase the ray's range, telling him he's helping the government develop this new weapon. Speavy spills the beans to Prof. Lewis and his daughter Madeleine,and Morgan threatens to implicate them in his crimes unless they cooperate. Morgan kills Speavy when he tries to warn Renfrew, but when Madeleine stows away on board the doomed plane Renfrew is piloting, will the crooks be able to make Prof. Lewis use the power ray to bring the plane down?
An army gold shipment and its escort vanish in the Ozarks, prompting accusations of theft and desertion but frontiersman Old Shatterhand and Apache chief Winnetou help solve the mystery of the missing army gold.
After striking gold in Alaska, the romantic George sends his womanizing partner Sam to bring his fiancée up from Seattle. When Sam finds that she has already married, he returns instead with Angel, a dancer originally from France.
When Temple's miners strike gold they send Jake to file the claim. Dana is in the Recorder's office and overhears. He and his men kill Jake and forge new deeds. Now owning everything Dana tries to kick the Temple group off their land. But Jack and sidekick Lucky are on hand and plan to help them fight back.
A young woman arrives in the western town of Headstone and helps the locals outsmart a gang of outlaws.
A widow hires an ex-gambler to retrieve gold bars from a sunken river boat in Colorado and discreetly return them to the Federal Mint, from where they had been stolen by her dead husband.
A part-Indian mining engineer looks for gold in an Arizona ghost town with his socialite bride.
Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.
A study in greed in which treasure hunters seek a shipment of gold buried in Death Valley.
The conflict between a railroader and a stage line owner is being aggravated by bad guys who are sabotaging both sides. Roy and Gabby mediate the conflict and expose the bad guys.
A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.
Stage line owner Brent has his men robbing Halliday stages and when his manager Waring learns of it, Brent has him killed. Jeff Waring arrives and takes his uncle's job. He soon learns what's happening and the Durango Kid goes into action. This keeps Halliday going and gives them a chance to get the mail contract by winning the stagecoach race.