When her mother dies, wheel-chair bound Winnie Brady is taken in by shopkeeper and neighbor "Uncle" Joe Carmine. Joe convinces Father Ryan to let him informally adopt her. Joe and Winnie live together with Tommy Devlin and his grandmother, Mrs. Devlin, and a dog Winnie names Muriel. Joe sells his shop to pay for an unsuccessful operation on Winnie's legs. This bankrupts Carmine, who then earns a meager living selling fruits and vegetables on the streets. Winnie is sent to live in an orphanage, and Carmine is discouraged from continuing his relationship with her. Carmine is so distraught by grief that he slowly begins to die. Winnie is brought to him by Father Ryan, and she finds the strength to stand and walk to his bedside and sings his favorite song, "Santa Maria." Later, after Winnie has acquired full use of her legs, Joe, in his new catering truck, takes the children on a picnic in the country.
The friendship between two orphans endures even though they grow up on opposite sides of the law and fall in love with the same woman.
Former P.O.W. Jack Calgrove moves Heaven and Earth to be reunited with his children following the Civil War. After returning home, Jack discovers that his wife has tragically died and his children, presumed to be orphans, are heading deep into the West on a train crossing enemy lines, with the intent of being placed into new homes. Calgrove and another soldier team up with a troop of Native American sharpshooters and a freed slave as they try to stop the train.
When Ruby and Rhett's parents are killed in a car accident, their carefree teenage lives are suddenly shattered. Moving to an incredible house in Malibu with the Glasses', old friends of the family, seems to be the beginning of a new life for them.
Annie, left orphaned after the death of her mother, goes to live in an orphanage where she tells her fellow orphans stories of ghosts and goblins. The matron of the orphanage finds Annie's closest relative, the abusive Uncle Thomp. Her uncle who puts her to hard work doing hard labor on his farm, belittling her all the while. Big Dave, a neighbor and tough cow-poke sees this and comes to her aid. Dave becomes her protector. Eventually Annie goes to live with Squire Goode and his large family. There, she entertains the children of the household with her stories, but sees her abusive aunt and uncle as her chief tormentors. She tells stories of how the goblins will take away the children if they are not good. Each story she tells is illustrated. War breaks out and Dave, who Annie adores, enlists. Uncle Thomp, hearing that Dave has been killed in action, takes pleasure in telling Annie the news. Broken-hearted, Annie falls ill and dies in bed, surrounded by family.
An actress becomes taken with Hitty, a young orphan prone to dreaming. Julie soon finds out that she is ill and has only a short time to live. She decides to adopt the child so that her husband Bill will not be alone when she dies. Unfortunately, Bill is not charmed by Hitty.
A sensitive girl is sent to an all-girls boarding school and develops a romantic attachment to one of her teachers.
Freckles, a one-armed orphan tired of being tormented by others runs away eventually finding a place as a watchman in the timber camp, The Limberlost. He falls in love with Angel but feeling unworthy of her keeps his feelings silent until a near catastrophic incident reveals the bond between them.
After a harsh childhood, orphan Jane Eyre is hired by Edward Rochester, the brooding lord of a mysterious manor house to care for his young daughter.
Things seem pretty bad for a young girl living a "hard-knock life" in an orphanage. Fed up with the dastardly Miss Hannigan, Annie escapes the run-down orphanage determined to find her mom and dad. It's an adventure that takes her from the cold, mean streets of New York to the warm, comforting arms of bighearted billionaire Oliver Warbucks - with plenty of mischief and music in between.
Caroline, a young waitress who seems to have bad taste in men, is on her way home one night when thugs attempt to rape her. Adam, the mysterious busboy who works at the same diner, helps fight off the assailants, and she begins a relationship with him -- but not all their fellow Minnesotans are happy for them. Meanwhile, the couple face their own difficulties when Caroline finds about Adam's past, including his unique health condition.
A runaway orphan, young Sonora, persists in a menial job mucking stables in Doc Carver's travelling stunt show. Her great wish is to become a death-defying "diving girl," but Doc refuses her pleas. Undaunted, Sonora's gutsy resolve finally convinces him to give her a break. On the brink of stardom, however, a cruel twist of fate threatens to destroy her dream.
In November 1918, a few days before the Armistice, when Lieutenant Pradelle orders a senseless attack, he causes a useless disaster; but his outrageous act also binds the lives of two soldiers who have nothing more in common than the battlefield: Édouard saves Albert, although at a high cost. They become companions in misfortune who will attempt to survive in a changing world. Pradelle, in his own way, does the same.
In the heady days of the 1968 Prague Spring, a group of Czechoslovak Radio journalists risk not just their careers but their lives to distribute independent news amidst national and regional tumult. Orphaned brothers Tomáš and Pája are caught in the struggle for freedom. The elder, Tomáš, is a radio technician working at the station committed to defying the Communist Party’s censorship, overwhelming propaganda, and police harassment. When security forces pressure him to spy for them, Tomáš finds himself in a bind where he has to choose between betraying his colleagues or protecting Pája.
After the accidental death of his son on a racetrack, Edward Milan, a wealthy industrialist, asks his nephew to find his grandson, who has been living in an orphanage for eleven years and whose existence he has just learned. But the boy, named Martineau, is suspicious of the police since he has been unjustly accused of shoplifting. He runs away when the two uniforms in charge of taking him back to his grandfather's house appear. He manages to find lodging with an old lady, a kleptomaniac at times, then with a theater prop master who is persecuted by his fiancée and finally with a lonely veterinarian.
Shipped off to a Romanian orphanage to finish his sentence, a British criminal finds romance but also discovers corruption inside the facility.
During a time of robber barons, child labor, and rising industry, two orphan girls get a little help from their unexpected guardian angels who turn the tide of events and change their lives forever.
Homer is an orphan who was never adopted, becoming the favorite of orphanage director Dr. Larch. Dr. Larch imparts his full medical knowledge on Homer, who becomes a skilled, albeit unlicensed, physician. But Homer yearns for a self-chosen life outside the orphanage. What will Homer learn about life and love in the cider house? What of the destiny that Dr. Larch has planned for him?
When 9-year-old orphan Oliver Twist dares to ask his cruel taskmaster, Mr. Bumble, for a second serving of gruel, he's hired out as an apprentice. Escaping that dismal fate, young Oliver falls in with the street urchin known as the Artful Dodger and his criminal mentor, Fagin. When kindly Mr. Brownlow takes Oliver in, Fagin's evil henchman Bill Sikes plots to kidnap the boy.
A Texan traveling across the wild West bringing the news of the world to local townspeople, agrees to help rescue a young girl who was kidnapped.