Jim Harvey is hired to guard a small wagon train as it makes its way west. The train is attacked by Indians and Harvey, hoping to persuade Aguila, the chief, to call off the attack due to Harvey's having saved his son's life, leaves the train to negotiate. He is captured and the rest of the train is wiped out except for two sisters. Escaping and showing up in town later, Harvey is nearly hanged as a deserter, but gets away. Eventually caught by the sheriff and his posse, they are attacked by Indians. This time the Indians are defeated and Aguila, captured and dying, reveals the identity of the white man who engineered the initial attack on the wagon train, just as the perpetrator rides up behind them.
Stony's brother George has been accused of murder and the Mesquiteers have returned to prove his innocence. But they find that Harvey rules the town along with his stooge Sheriff Gray and that George won't get a fair trial.
Banker Mason is after the ranchers land so he can resell it to the railroad for a profit. He has the railroad agent killed and replaces him with his stooge who then offers even less than Mason. But Rocky eventually suspects Mason and when Bill Anderson informs him the agent is a fake, they head out after Mason
The Johnny Mack Brown West of Wyoming concerns the efforts by cattle baron Simon (Stanley Andrews) to prevent the opening up of the rang to homesteaders. Government agent Brown comes calling when Simon begins resorting to cold-blooded murder. The leading lady is Gail Davis, a few years shy of her Annie Oakley TV stardom. Surprisingly, West of Wyoming contains none of the comedy relief that had characterized earlier Johnny Mack Brown oaters.
Just before the Civil War (but after the South has seceded), Southern saboteurs try to prevent railroad construction from crossing Kansas to the frontier; army captain Nelson is sent out to oppose them. As the tracks push westward, Nelson must contend with increasingly violent sabotage, while trying to romance the foreman's pretty daughter Barbara.
A Mexican bandit is about to be executed in the United States, so his brother takes over a train and holds the passengers as hostages unless his brother is released. Now both the Americans and Mexicans are baffled as to what to do. One of the passengers — who wrote the letter for their captor — has a suggestion: call mercenaries Hank Brackett and Johnny Reech. They do, and as expected they do come up with a plan, but the president of the railroad is not sure if it will work.
A wagon train heads for Denver with a cargo of whisky for the miners. Chaos ensues as the Temperance League, the US cavalry, the miners and the local Indians all try to take control of the valuable cargo.
Lt. Col. Kirby Yorke is posted on the Texas frontier to defend settlers against depredations of marauding Apaches. Col. Yorke is under considerable stress by a serious shortage of troops of his command. Tension is added when Yorke's son (whom he hasn't seen in fifteen years), Trooper Jeff Yorke, is one of 18 recruits sent to the regiment.
Cole Thornton, a gunfighter for hire, joins forces with an old friend, Sheriff J.P. Harrah. Together with a fighter and a gambler, they help a rancher and his family fight a rival rancher that is trying to steal their water.
A mysterious preacher protects a humble prospector village from a greedy mining company trying to encroach on their land.
Buck Roberts is leading a wagon train of railroad supplies and Jim Corkle and his henchman Loder are out to stop them by using white men dressed as Indians for the attacks.
A western bandit is reformed by his love for a little girl.
A weary gunfighter attempts to settle down with a homestead family, but a smouldering settler and rancher conflict forces him to act.
This Western is a pilot for the series "The Iron Horse," in which a dapper frontier gambler wins a railroad line in a poker game and has his hands full holding it from the clutches of various conniving bad guys.
After the train station clerk is assaulted and left bound and gagged, then the departing train and its passengers robbed, a posse goes in hot pursuit of the fleeing bandits.
Female outlaw helps lawmen trap railroad bandits.
The simple story has the pair coming to the rescue of peace-loving Mormons when land-hungry Major Harriman sends his bullies to harass them into giving up their fertile valley. Trinity and Bambino manage to save the Mormons and send the bad guys packing with slapstick humor instead of excessive violence, saving the day.
Tom Kenyon and his sidekick Pierre La Farge are hired by rancher Mike O'Day who, with his daughters Toni and Sugar, provides wild horses for the government remount station.
Jubal Troop is a cowboy who is found in a weakened condition, without a horse. He is given shelter at Shep Horgan's large ranch, where he quickly makes an enemy in foreman Pinky, a cattleman who accuses Jubal of carrying the smell of sheep.
About to marry Jim Plummer, Kate Foley runs off to Nevada when Ed Bagley convinces her a quick fortune can be made robbing gold shipments that are being transported by the railroad. In Bannock City she meets reformed-bandit Frank Plummer, posing as Frank Norris, brother of Jim Plummer, who has being going straight and working as an express shipment guard. Jim also shows up and plans a robbery by stealing a train and hiding it in an abandoned tunnel. The two brothers are on opposite sides of the law with the now-reformed Kate caught in the middle.