In Apache territory, a supply Army column heads for the next fort, an ex-scout searches for the killer of his Native wife, and a housewife abandons her husband to rejoin her Apache lover's tribe.
On the run after committing murder, an accountant encounters a strange Native American man who prepares him for his journey into the spiritual world.
In the mid-19th century, California, a Mexican territory, became part of the United States. Faced with the possibility of being dispossessed of his land by the new authorities, Don César de Echagüe, a Spanish nobleman, asks his son César, a capricious and insufferable fop, for help.
A posse discovers a trio of men they suspect of murder and cow theft and are split between handing them over to the law or lynching them on the spot.
When Sheriff Bill marries, he moves to another village to lead a more peaceful life. His replacement is killed by Colorado Charlie and his gang. The town sends for Bill, who returns unarmed because his wife has hidden his gun. When Colorado Charlie demands a shoot-out, Bill's wife relents and gives him back his weapon After Bill kills the bandit, his wife agrees to his return as sheriff.
A gringo gunman and two Mexican families fight a bandit and his gang.
A gang of bandits takes control of Tucson in preparation for the arrival of a consignment of gold, with only a band of voluntary soldiers trying to outwit them and save the town.
Major Bower’s wife tells her lover Chaliko where her father’s fortune is hidden. When the major finds out he murders her and with his gang, goes after Chaliko.
When Black Bill's father is murdered and his uncle kidnapped, he sets out in pursuit of the perpetrators.
The story takes place in Kansas, just after the Civil War. Wild Bill Hickok is summoned from Dodge City to Abilene, there to neutralize a crooked political machine. Hickok is aided every step of the way by Tex Rawlings, a seemingly harmless drifter who is appointed sheriff after proving his prowess with his six-guns.
Hayden enters the lawless prairie in which criminals have had free reign to manipulate the innocent settlers.
When Rangers Lucky and his brother chase outlaws, the brother is killed. To find the killer Lucky quits the Rangers and robs the bank. This gets him into the outlaw gang where he learns of their next raid. Sneaking out at night he tells his girl friend who must now convince the Sheriff that Lucky is not an outlaw and that he must sent his men out to catch the gang.
William Munny is a retired, once-ruthless killer turned gentle widower and hog farmer. To help support his two motherless children, he accepts one last bounty-hunter mission to find the men who brutalized a prostitute. Joined by his former partner and a cocky greenhorn, he takes on a corrupt sheriff.
A young man takes the job as sheriff after the sheriff is killed trying to stop a lynch mob. Gunfighters and bounty hunters control the town. It looks like the end, until a man with a loss of memory drifts into town.
After blaming Britt for his wife's decision to stay with the Native Americans who captured her, an abusive husband organizes a party of vigilantes to accompany him into Indian territory.
As the west rapidly becomes civilized, a pair of outlaws in 1890s Wyoming find themselves pursued by a posse and decide to flee to South America in hopes of evading the law.
The Man With No Name enters the Mexican village of San Miguel in the midst of a power struggle among the three Rojo brothers and sheriff John Baxter. When a regiment of Mexican soldiers bearing gold intended to pay for new weapons is waylaid by the Rojo brothers, the stranger inserts himself into the middle of the long-simmering battle, selling false information to both sides for his own benefit.
Johnny Mack Brown substitutes brains for brawn during most of Texas City. Cast once more as a U.S. marshal, Johnny investigates when several government gold shipments are hijacked. Someone has been tipping of the outlaws as to when and where the supposedly secret shipments will take place. The principal suspect is dishonorably discharged cavalry officer Kirby (James Ellison), but Johnny has a gut feeling that Kirby is innocent on all counts.
A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.
Johnny Mack Brown's Universal western series was drawing to a close when Cheyenne Roundup was released in mid-1943. Brown is herein cast in a dual role, as honest Gils Brandon and his less-than-honest brother Buck. Pursued by lawman Steve Rawlins (Tex Ritter), Buck tries to pass himself off as the upright Gils.