In the year 2035, convict James Cole reluctantly volunteers to be sent back in time to discover the origin of a deadly virus that wiped out nearly all of the earth's population and forced the survivors into underground communities. But when Cole is mistakenly sent to 1990 instead of 1996, he's arrested and locked up in a mental hospital. There he meets psychiatrist Dr. Kathryn Railly and the son of a famous virus expert who may hold the key to the Army of the 12 Monkeys; thought to be responsible for unleashing the killer disease.
In 1850s Louisiana, the willfulness of a tempestuous Southern belle threatens to destroy all who care for her.
Twenty-eight days after a killer virus was accidentally unleashed from a British research facility, a small group of London survivors are caught in a desperate struggle to protect themselves from the infected. Carried by animals and humans, the virus turns those it infects into homicidal maniacs -- and it's absolutely impossible to contain.
On a stormy night, young Jim, who transports a luxury car from Chicago to California to deliver it to its owner, feeling tired and sleepy, picks up a mysterious hitchhiker, who has appeared out of nowhere, thinking that a good conversation will help him not to fall asleep. He will have enough time to deeply regret such an unmeditated decision.
When virtually all of the residents of Piedmont, New Mexico, are found dead after the return to Earth of a space satellite, the head of the US Air Force's Project Scoop declares an emergency. A group of eminent scientists led by Dr. Jeremy Stone scramble to a secure laboratory and try to first isolate the life form while determining why two people from Piedmont - an old alcoholic and a six-month-old baby - survived. The scientists methodically study the alien life form unaware that it has already mutated and presents a far greater danger in the lab, which is equipped with a nuclear self-destruct device designed to prevent the escape of dangerous biological agents.
Following a brutal war, former soldier Van toils in a mine controlled by the ruling empire. One day, his solitary existence is upended when a pack of wild dogs carrying a deadly and incurable disease attack, leaving only Van and a young girl named Yuna as survivors. Finally free, the pair seek out a simple existence in the countryside but are pursued by nefarious forces. Intent on protecting Yuna at all costs, Van must uncover the true cause of the plague ravaging the kingdom—and its possible cure.
Hideo Suzuki is a 35-year-old mangaka assistant, whose life seem to be stuck around his exhausting but low-paying job, unfulfilled dreams, strange hallucinations and unsatisfying relationships. He sees himself as a supporting character in his own life, has low self-esteem, resulting in frustration. One day, the world as Hideo knows it is shattered by the presence of a disease that turns people into homicidal maniacs, whose first instinct is to attack and devour the nearest human.
Charles Brady and his mother, Mary, are the last of a dying breed whose needs are not of this world. They are Sleepwalkers - able to stay alive only by feeding on the life-force of the innocent, but destined to roam the earth, avoiding discovery while searching for their next victim. That search takes them to the sleepy little town of Travis, Indiana, where beautiful teenager Tanya Robertson is about to become an unwilling pawn in their nightmarish fight for survival.
While executing an armored car heist in Los Angeles, icy crook Dave Purvis shoots policeman Lt. Phillips before he and his cronies make off with the loot. Thinking he got away scot-free, Purvis collects his money-crazy mistress, Yvonne, then disposes of his partners and heads out of town. What Purvis doesn't know is that Phillips' partner, tough-as-nails Lt. Cordell, is wise to the criminal's plans and is closing in on his prey.
Food shortages during a pandemic force recently widowed George to stray far from home to survive. A simple purchase of rations derails when George stumbles upon a Shopkeeper's secret, placing them in mortal jeopardy.
Citizens of a small town are infected by a biological weapon that causes its victims to become violently insane. As uninfected citizens struggle to survive, the military readies its own response.
As an epidemic of a lethal airborne virus - that kills within days - rapidly grows, the worldwide medical community races to find a cure and control the panic that spreads faster than the virus itself.
Questioned as a murder suspect, solid (but drunk) citizen Al Willis attacks his police questioners, is beaten, and swears vengeance against them. Next night, Lieut. Parks is murdered; Willis is the only suspect in the eyes of tough Chief Conroy, who pursues him doggedly despite lack of evidence. The obsessed Conroy is dismissed from the force, but continues to harass Willis, who flees to a sleazy town on the Mexican border. Of course, Conroy follows. But which is crazy, Conroy or Willis?
An unprecedented epidemic of rabies is breaking out in the taiga. Infected wolves become more and more ferocious, and even the slightest bite brings certain death. At the same time, a desperate father decides to forcibly isolate his son in one of the hunting lodges in order to save him from addiction. Soon, he and several local residents will have to fight not only with a rabid pack, but also with the most dangerous predator of the forest.
Joe Don Baker plays a gambler who is framed for a crime he did not commit. A corrupt legal system leads him into a plea bargain and four years behind bars. By the time he gets out of prison, he's determined to put together the pieces of his frame-up and dole out the justice he was denied to those responsible.
Inspectors for the U.S. Public Health Service try to track down the cause of a rash of mysterious ailments suddenly appearing among the general populace.
A British medical doctor fights a cholera outbreak in a small Chinese village, while also being trapped at home in a loveless marriage to an unfaithful wife.
An LA police officer is murdered in the onion fields outside of Bakersfield. However, legal loopholes could keep his kidnappers from receiving justice, and his partner is haunted by overwhelming survivor's guilt.
A doctor's already-shaky marriage is tested to an even greater extent when he has to contend with a smallpox epidemic.
Washington, D.C. psychologist Carol Bennell and her colleague Dr. Ben Driscoll are the only two people on Earth who are aware of an epidemic running rampant through the city. They discover an alien virus aboard a crashed space shuttle that transforms anyone who comes into contact with it into unfeeling drones while they sleep. Carol realizes her son holds the key to stopping the spread of the plague and she races to find him before it is too late.