While the Civil War rages on between the Union and the Confederacy, three men – a quiet loner, a ruthless hitman, and a Mexican bandit – comb the American Southwest in search of a strongbox containing $200,000 in stolen gold.
An aging group of outlaws look for one last big score as the "traditional" American West is disappearing around them.
As the west rapidly becomes civilized, a pair of outlaws in 1890s Wyoming find themselves pursued by a posse and decide to flee to South America in hopes of evading the law.
Hell's Crown, a town where law and order are as scarce as preachers, is ruled by "Chuck" Wells, a former gun man. He has a dupe in Blaze, the terror of the town, and holds him by keeping him well supplied with money. A sheriff is appointed at Carson City on account of the horse rustlers.
Will Penny, an aging cowpoke, takes a job on a ranch which requires him to ride the line of the property looking for trespassers or, worse, squatters. He finds that his cabin in the high mountains has been appropriated by a woman whose guide to Oregon has deserted her and her son. Too ashamed to kick mother and child out just as the bitter winter of the mountains sets in, he agrees to share the cabin until the spring thaw. But it isn't just the snow that slowly thaws; the lonely man and woman soon forget their mutual hostility and start developing a deep love for one another.
A former gunslinger is forced to take up arms again when he and his cattle crew are threatened by a corrupt lawman.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
Will Kane, the sheriff of a small town in New Mexico, learns a notorious outlaw he put in jail has been freed, and will be arriving on the noon train. Knowing the outlaw and his gang are coming to kill him, Kane is determined to stand his ground, so he attempts to gather a posse from among the local townspeople.
Dinner time in a remote home of a prairie family turns nightmarish when a band of blood spattered outlaws break through the front door in search of food, horses, and women. Nothing is as it seems in this constantly twisting genre bender.
Wild Bill Hickock and Cannonball help two young people in love and bring the murderer of Cannonball's father to justice.
When Tasker kills Roy Rogers he takes one of his young sons. Fifteen years later the other son Roy arrives buying a ranch in the valley where Tasker now controls the water supply. Roy organizes the ranchers for a showdown with Tasker not knowing that his brother is Tasker's chief henchman.
Gene is the foreman at the ranch owned by wealthy rodeo owner Maureen. She will lose her rodeo contract unless sales improve.
Tex and his sidekicks arrive to help out his friend Jeffers, a railroad owner, only to find that he has been killed. They quickly run into trouble with an outlaw gang in their attempt to find the mysterious ghost train that supposedly runs on Jeffer's line.
A renowned former army scout is hired by ranchers to hunt down rustlers but finds himself on trial for the murder of a boy when he carries out his job too well. Tom Horn finds that the simple skills he knows are of no help in dealing with the ambitions of ranchers and corrupt officials as progress marches over him and the old west.
In the midst of the Civil War, Lassiter has a plan to get control of California. Working out of St. Joseph, he plans to send forged messages to the troops on the west coast via Pony Express. First he attempts to bribe Pony Express ride Roy Rogers. When Roy refuses he turns to the outlaw Johnson and his gang and this leads to trouble.
A feud between the families of Gourd and Fork Ranches
Peterson has a plan to obtain all the ranches in the valley. He gives Carson a phony Spanish land grant and has him pose as the Mexican owner. When Fred and Fuzzy have their cattle stolen by Peterson's men, they quickly become involved in the scheme.
Atkins is the boss of one of the Pony Express relay stations. He has been causing trouble and is replaced with Cal Sheridan. Atkins now gets the Richard brothers to raid one of the relay stations and they kill Norma's father. Cal sees that the horse of one of the raiders has a broken shoe and Norma sets out to find that horse.
Roy returns home to fine a range feud between the cattlemen and the sheepmen. When his friend is killed he finds the rifle had a defective pin. He learns the rifle belongs to a ranch hand named Barker and that a third party has caused the feud. When he captures outlaws trying to blow up a dam, he claims Barker was the killer. But Barker has switched rifles and the outlaws now accuse Roy and Roy finds himself in trouble.
Gene Autry hunts bank robbers Al Bartlett and Trot Lucas with his old friend Mike. Bartlett, to throw off his pursuers, kills Trot and his own brother. When Kitty Bartlett comes to town claiming to be the slain Bartlett's widow, Gene has to save her from the irate townspeople who are not aware that her name isn't Bartlett but she really is the daughter of a law officer slain by Al Bartlett. Ben Luder, a local hood, tricks Bartlett back into town by saying he has to fixed to have Doc Larry Taylor do plastic surgery on him. En route they meet Doc and his assistant Helen Ellis and Ben's ruse is exposed. Bartlett kills Ben and forces Doc to drive him to the railroad. Gene, in a fight atop a runaway train, captures Bartlett.