Prologue

An old woman has died and her widower with dementia confesses to killing her. After this, the story goes back in time to show the events leading up to her death.

The adventures of married couple Henry and Nancy Clark, vexed by misfortune while in New York City for Henry's job interview.

Gail and Tom Hartman are struggling to stay together and decide to take a white-water rafting holiday adventure in Montana for their son Roarke's 10th birthday, only to meet up with a pair of mysterious men whose desperation grows, turning their vacation into a nightmare.

As she reaches her mid-thirties and quits her lucrative job, singleton Olivia finds herself unsure about her future and her relationships with her successful and wealthy friends. She begins to envy the security of her richer friends and, although their lives may seem easier, Olivia's friends have their problems too: screenwriters Christine and Patrick are unable to collaborate on their latest project, Jane and Aaron have lost the romance in their relationship, and Franny and Matt have difficulties handling the demands of parenthood.

A well-to-do husband who allows his wife to have affairs in order to avoid a divorce becomes a prime suspect in the disappearance of her lovers.

Alicia and Enrique are a young married couple somewhat distanced from each other. Their relationship is threatened when Carlota, a friend of Alicia's from long ago, comes to visit and stays with them for a while.

Have you ever sat by the phone wondering why he said he would call, but didn't, or you can't figure out why she doesn't want to sleep with you anymore, or why your relationship just isn't going to the next level... they're just not that into you. Gigi just wants a man who says he'll call—and does—while Alex advises her to stop waiting by the phone. Beth wants a proposal after years of a committed relationship with her boyfriend, Neil, who sees nothing wrong with the status quo. Janine's not sure if she can trust her husband, Ben, who can't quite trust himself around Anna. Anna can't decide between the sexy married guy, or her straightforward, no-sparks standby, Conor, who can't get over the fact that he can't have her. And Mary, who's found an entire network of loving, supportive men, just needs to find one who's straight.

A discount store clerk strikes up an affair with a stock boy who considers himself the incarnation of Holden Caulfield.

Ruth, an elderly lady with dementia, becomes lost within her own home. As she tries to find answers, she ends up losing herself further, confusing reality with memories of her past self.

Benjamin Morton's life changed forever the day he met the little girl next door. Ava was and always would be the girl of his dreams. From the innocence of a childhood friendship, through adolescent attraction, their love strengthens and grows. When life takes a turn neither of them expected, their entire future is called into question.

Young Augusten Burroughs absorbs experiences that could make for a shocking memoir: the son of an alcoholic father and an unstable mother, he's handed off to his mother's therapist, Dr. Finch, and spends his adolescent years as a member of Finch's bizarre extended family.

Five unmarried sisters make the most of their simple existence in rural Ireland in the 1930s.

An unsettling feeling overwhelms a small Hungarian town when two orthodox Jews arrive with a mysterious trunk. As residents begin to speculate on the purpose of the visit of these two strangers, order starts to crumble in town with some pursuing devious plans and others finding remorse in their hearts.

Architect Mark Wallace and his wife, Joanna, travel to France to meet with an affluent client. While there, they reflect on their first decade of marriage -- memories of when they first met, of courtship, and of road trips through the French countryside. As flirtation and playful quarreling turn to boredom with the banality of married life, the Wallaces struggle to rekindle their passion, while mutual infidelity threatens to tear them apart.

A poet falls in love with an art student, who gravitates to his bohemian lifestyle — and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.

After her much older husband forces a move to a suburban retirement community, Pippa Lee engages in a period of reflection and finds herself heading toward a quiet nervous breakdown.

As young French couple Gilles and Marion officially separate, we see, in reverse order, the milestone moments in their relationship: Gilles revealing his unfaithfulness at a tense dinner party; Marion giving birth to their premature son while Gilles is elsewhere; Gilles and Marion's joyous wedding; and, finally, the fateful moment when they meet as acquaintances at an Italian beach resort, and their love affair begins.

Young doctors mix romance with their careers in a big-city hospital.

Climbing aboard their mammoth recreational vehicle for a cross-country road trip to the Colorado Rockies, the Munro family – led by dysfunctional patriarch, Bob – prepares for the adventure of a lifetime. But spending two weeks together in one seriously small space has a way of cramping their style.

A mother and daughter dispute is resolved by the "Yaya sisterhood" - long time friends of the mother.