A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.
Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide to travel cross-country in search of spiritual truth.
Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.
A down-and-out Brooklyn detective is hired to track down a singer on an odyssey that will take him through the desperate streets of Harlem, the smoke-filled jazz clubs of New Orleans, and the swamps of Louisiana and its seedy underworld of voodoo.
People in the future live in a totalitarian society. A technician named THX 1138 lives a mundane life between work and taking a controlled consumption of drugs that the government uses to make puppets out of people. As THX is without drugs for the first time he has feelings for a woman and they start a secret relationship.
In 1973, 15-year-old William Miller's unabashed love of music and aspiration to become a rock journalist lands him an assignment from Rolling Stone magazine to interview and tour with the up-and-coming band, Stillwater.
A retired cop and his new partner must put their differences aside while investigating a drug ring.
Homer is an orphan who was never adopted, becoming the favorite of orphanage director Dr. Larch. Dr. Larch imparts his full medical knowledge on Homer, who becomes a skilled, albeit unlicensed, physician. But Homer yearns for a self-chosen life outside the orphanage. What will Homer learn about life and love in the cider house? What of the destiny that Dr. Larch has planned for him?
Yuri Orlov is a globetrotting arms dealer and, through some of the deadliest war zones, he struggles to stay one step ahead of a relentless Interpol agent, his business rivals and even some of his customers who include many of the world's most notorious dictators. Finally, he must also face his own conscience.
After her drug pusher boyfriend overdoses on heroin, a cabaret singer finds refuge from the authorities in a convent for fallen women.
When two brothers organize the robbery of their parents' jewelry store, the job goes horribly wrong, triggering a series of events that send them and their family hurtling towards a shattering climax.
Darren Aronofsky’s AFI short opens with angry slacker Dave sitting in a dreary, empty junkyard. Dave stares into space, sips beer, and beats the hell out of a cracked guitar. We quickly realize the emptiness of the dump parallels the emptiness of Dave’s life which consists of smoking weed, staring at television screens and watching school children. Dave’s friend Pete is shortly introduced, along with their friend, Ari, who despite calling her pals losers, doesn’t seem to accomplishing much herself. These three are going nowhere fast. They’re the amoebas of life… protozoa….
After getting into a car accident while drunk on the day of her sister's wedding, Gwen Cummings is given a choice between prison or a rehab center. She chooses rehab, but is extremely resistant to taking part in any of the treatment programs they have to offer, refusing to admit that she has an alcohol addiction.
In 1965, a young woman with dreams of becoming a writer has a son at the age of 15 and struggles to make things work with the drug-addicted father.
A New York press agent must scramble when his major client becomes embroiled in a huge scandal.
While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.
Pseudo-documentary style drama about drug addicts. In Kyiv, a dealer named Baroque receives an unknown psychedelic that opens access to another dimension.
A young police woman is faced with the difficulties between her responsibilities at work and her personal responsibilities.
Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.
After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.