Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
Elizabeth has just been through a particularly nasty breakup, and now she's ready to leave her friends and memories behind as she chases her dreams across the country. In order to support herself on her journey, Elizabeth picks up a series of waitress jobs along the way. As Elizabeth crosses paths with a series of lost souls whose yearnings are even greater than her own, their emotional turmoil ultimately helps her gain a greater understanding of her own problems...
Chrissy is a teen who spends all her time online. After being pushed to the brink by both of her parents, she steals her mom's car and runs away to pick up her internet boyfriend.
A retired farmer and widower in his 70s, Alvin Straight learns one day that his distant brother Lyle has suffered a stroke and may not recover. Alvin is determined to make things right with Lyle while he still can, but his brother lives in Wisconsin, while Alvin is stuck in Iowa with no car and no driver's license. Then he hits on the idea of making the trip on his old lawnmower, thus beginning a picturesque and at times deeply spiritual odyssey.
When Gelsomina, a naïve young woman, is purchased from her impoverished mother by brutish circus strongman Zampanò to be his wife and partner, she loyally endures her husband's coldness and abuse as they travel the Italian countryside performing together. Soon Zampanò must deal with his jealousy and conflicted feelings about Gelsomina when she finds a kindred spirit in Il Matto, the carefree circus fool, and contemplates leaving Zampanò.
In this loose adaptation of Shakespeare's "Henry IV," Mike Waters is a hustler afflicted with narcolepsy. Scott Favor is the rebellious son of a mayor. Together, the two travel from Portland, Oregon to Idaho and finally to the coast of Italy in a quest to find Mike's estranged mother. Along the way they turn tricks for money and drugs, eventually attracting the attention of a wealthy benefactor and sexual deviant.
Jake Blues, just released from prison, puts his old band back together to save the Catholic home where he and his brother Elwood were raised.
A quintet of cabbies in five cities and their remarkable fares on the same eventful night.
When car dealer Charlie Babbitt learns that his estranged father has died, he returns home to Cincinnati, where he discovers that he has a savant older brother named Raymond and that his father's $3 million fortune is being left to the mental institution in which Raymond lives. Motivated by his father's money, Charlie checks Raymond out of the facility in order to return with him to Los Angeles. The brothers' cross-country trip ends up changing both their lives.
After learning that a boy their age has been accidentally killed near their rural homes, four Oregon boys decide to go see the body. On the way, Gordie, Vern, Chris and Teddy encounter a mean junk man and a marsh full of leeches, as they also learn more about one another and their very different home lives. Just a lark at first, the boys' adventure evolves into a defining event in their lives.
A boy and a girl who have just met transport a corpse on request to the north of Mexico. When the police discover them at a routine check, they are forced to flee. Forced to team up, they will abandon their secrecy and mistrust while trying to assert his only heritage: a dead man who they only know is worth money if they manage to take him to his destination.
Corporate billionaire Edward Cole and working class mechanic Carter Chambers are worlds apart. At a crossroads in their lives, they share a hospital room and discover they have two things in common: a desire to spend the time they have left doing everything they ever wanted to do and an unrealized need to come to terms with who they are. Together they embark on the road trip of a lifetime, becoming friends along the way and learning to live life to the fullest, with insight and humor.
Lloyd and Harry are two men whose stupidity is really indescribable. When Mary, a beautiful woman, loses an important suitcase with money before she leaves for Aspen, the two friends (who have found the suitcase) decide to return it to her. After some "adventures" they finally get to Aspen where, using the lost money they live it up and fight for Mary's heart.
A naive Canadian barber who knows US popular culture inside and out meets a flamboyant roadie who needs someone to drive her and her "brother's" corpse from Thunder Bay, Ontario to New Orleans. Chaos ensues after the barber agrees to drive her, the corpse, and the drugs stashed within all the way.
Once called "Father Frank" for his efforts to rescue lives, Frank Pierce sees the ghosts of those he failed to save around every turn. He has tried everything he can to get fired, calling in sick, delaying taking calls where he might have to face one more victim he couldn't help, yet cannot quit the job on his own.
In turn-of-the-century Mississippi, an 11-year-old boy comes of age as two mischievous adult friends talk him into sneaking the family car out for a trip to Memphis and a series of adventures.
Jerry Welbach, a reluctant bagman, has been given two ultimatums: The first is from his mob boss to travel to Mexico and retrieve a priceless antique pistol, known as "the Mexican"... or suffer the consequences. The second is from his girlfriend Samantha to end his association with the mob. Jerry figures alive and in trouble with Samantha is better than the more permanent alternative, so he heads south of the border.
In 1980, an American journalist covering the Salvadoran Civil War becomes entangled with both the leftist guerrilla groups and the right-wing military dictatorship while trying to rescue his girlfriend and her children.
Barnaby and Maxine Pierce, an embattled married couple in Connecticut, are on the verge of divorce. Their son is getting married in California and they decide to drive across the country to attend. Along the way, as they visit family and friends, they reflect on their tattered relationship and the events that transpired to create the estrangement.
Turo is stuck in a small village and the best thing in his life is being the lead vocalist for the amateur metal band Impaled Rektum. He and his bandmates have practiced for 12 years without playing a single gig. The guys get a surprise visitor from Norway -- the promoter for a huge heavy metal music festival -- and decide it's now or never. They steal a van, a corpse, and even a new drummer to make their dreams a reality.