After their first adventure with the Hot Tub Time Machine, Lou and Nick are living very well off their ill-gotten gains, while Jacob still cannot rely on Lou to be a positive role model. When an unknown assailant breaks into Lou's mansion and shoots him, Nick and Jacob take him for another trip in the hot tub. They emerge in the year 2025, where they must figure out who shot Lou and prevent it from happening again.
Nils and his two best friends are invited to a 25 year reunion for their student years. Nils is given the task of holding the main speech. This comes at a bad time. He is troubled with his self consciousness, eyesight, hemorrhoids and age bothering him.
Blue-collar Paulie prepares for fatherhood and his forthcoming wedding to Sue by hanging out with his groomsmen. Brother Jimbo, cousin Mike, and his pals fill the reunion with drinking, boys-will-be-boys antics and a few unexpected personal confessions. But, when the bonding devolves into accusations and regret, Paulie has to decide whether he's ready to tie the knot and take this big step into adulthood.
Masaki, a baseball player and gas-station attendant, gets into trouble with the local Yakuza and goes to Okinawa to get a gun to defend himself. There he meets Uehara, a tough gangster, who is in serious debt to the yakuza and planning revenge.
Tommy has lost his job, his love and his life. He lives in a small apartment above the Trees Lounge, a bar which he frequents along with a few other regulars without lives. He gets a job driving an ice cream truck and ends up getting involved with the seventeen-year-old niece of his ex-girlfriend. This gets him into serious trouble with her father.
Sometimes New Year eve can bring a lot of surprises...
During a wild vacation in Las Vegas, career woman Joy McNally and playboy Jack Fuller come to the sober realization that they have married each other after a night of drunken abandon. They are then compelled, for legal reasons, to live life as a couple for a limited period of time. At stake is a large amount of money.
Returning home with his father after a shopping expedition, Wong Fei-Hong is unwittingly caught up in the battle between foreigners who wish to export ancient Chinese artifacts and loyalists who don't want the pieces to leave the country. Fei-Hong must fight against the foreigners using his Drunken Boxing style, and overcome his father's antagonism as well.
A pair of adventurers try to track down an ancient Aztec/Mayan/Egyptian/Apache horde of gold.
Tadeoz Toroshelidze is the most reknowned wine drinker in the whole area. Once he even won a drinking horn in a competition that has rested in his house ever since.
Randy Feltface teams up with a typewriter in this hilarious hour of spoken word and gratuitous arm movements.
Ritchie Spencer and his friends have a problem. They are the only four members of their fraternity, and they are all graduating. They must find a way to bring in more members before they leave, and dodge their way around the rival jock fraternity.
Bob McGraw is in his 12th year of college, goofing his way through life. Bob, Irwing, Gonzer and Max are the four losers forced and bribed to represent their university in an intercollegiate raft race. Forced and bribed into this role, they make some friends, the lovely Heather Merriweather, but mostly enemies, among others a whole team of marines, and preppy IVY-leaguers determined to win.
After New York City firefighter Terry Lynch is unable to receive any compensation for an injury incurred during the off-duty rescue of a young girl, he grows suicidal. Furious, his brother Jimmy attempts to have Mayor Tyler intervene, but the corrupt politician instead denounces Terry as a drunk. Determined to get justice, Jimmy begins a graffiti campaign of embarrassing slogans mocking the mayor, which soon captivates the city.
In a bleak Inverness midwinter, Luisaidh is careening off the rails after the suicide of her best friend. She medicates her misery with joyless sex, chips and a belief in the power of positive drinking. Surrounded by bittersweet memories, she struggles to find someone to talk to or some reason to make life worthwhile at the most stressful time of the year.
Having thought that monogamy was never possible, a commitment-phobic career woman may have to face her fears when she meets a good guy.
Office temp Charlotte Cantilini thinks she's found Mr. Right when she starts dating gorgeous surgeon Dr. Kevin Fields. But there's a problem standing in the way of everlasting bliss: Kevin's overbearing and controlling mother, Viola. Fearing she'll lose her son's affections forever, Viola decides to break up the happy couple by becoming the world's worst mother-in-law.
During World War II, an innkeeper vows to abstain from alcohol for the sake of his family. Years later, as they thrive in Normandy, his resolve is tested by a charming advertising professional who loves to drink.
Madeline is married to Ernest, who was once arch-rival Helen's fiance. After recovering from a mental breakdown, Helen vows to kill Madeline and steal back Ernest. Unfortunately for everyone, the introduction of a magic potion causes things to be a great deal more complicated than a mere murder plot.
Two sets of two college guys spend a spring break together in Fort Lauderdale, Florida. There they have lots of fun in and out of the sun.