The movie deals with the trials and tribulations of multiple disconnected characters trying to find meaning in the spiritual and super natural experiences they have. The intertwining story threads include a baker (Kunchako) going to meet his pregnant wife (Bhama), a moneylender (Manoj K Jayan) with an imaginary friend (Saiju Kurup), an atheist policeman (Kalabhavan Mani) who is unfaithful to his wife, an old man (Janardhanan) whose daughter (Anju Aravind) gets into a road accident, a photographer (Joy Mathew) and a college girl (Sarayu) trying to prank her room mates.
When Guptan, a college lecturer, gets killed, the police suspect Gabriel to be the murderer. A girl takes help from her brothers, who are famous lawyers, in proving his innocence.
Arun finally finds love in Swati after a long luckless search. They get married and soon their parents and their massive egos start interfering with their life. The problems worsen when a huge cupboard arrives as a gift from Swati's parents.
Afzal is happy after his uncle helps him to set up his mobile shop. However, things take an unexpected turn when Azhagarsamy gifts him a virus-infected mobile application.
Attempting to kickstart his career, Karthik makes a documentary on Alzheimer's disease. His subject, Malathi Menon, lives in a small town outside Harippad with her daughter Athira. Karthik and his team arrive at Malathi's place and start noticing Malathi's unexplainable behavior, where she starts speaking in an ancient language and scribbling on certain pictures.
George Vadakkan is the quintessential prodigal son of a priest, who wished he followed the father’s path. His friends and George generally hang out at Mathayi Parambu, a public playground cum hangout space of the area. How the park plays a part in setting his life straight is the core of the pooram.
Pauly belongs to a well off family in a rural village of Kerala. A politician by profession, he does many helpful activities for the benefit of poor people in the village. Sukumaran Nair a member of the opposition party, tries to disrupt whatever Pauly does. They have been enemies from a very long time. Things become worse when Pauly falls in love with Sukumaran Nair's daughter Aswathy
An immensely rich farmer lives peacefully with his family in Pala and has no idea about the hectic metro life. He gets introduced to it when he hides a love-stricken couple in his house.
Six young friends in the small town of Angamaly tries their luck by starting a pork business lead by Vincent Pepe. They initially strike a business deal with Rajan and Ravi despite the duo having killed a close friend of theirs in a gang fight. Vincent is in love with Sakhi and plan to immigrate abroad with her. But their plans hit a road bump as the deal with the gangsters hits some road bumps.
Three friends decide to hire a prostitute on the day of the Aatukaal Pongala - a Hindu festival in Trivandrum - when their wives are busy.
Prince, a dog trainer, faces an awkward situation when his pet dog Diana acts in a film alongside his ex-lover, an actress who shares the same name as the dog.
Meenukutty is an ardent Mohanlal fan, whereas her husband, Sethumadhavan, struggles with the usual family life due to Meenukutty's celebrity worship syndrome.
Sassi, a pompous man, uses unfair means to create a name for himself in the society. When he finds out that he is terminally ill, he gets a special coffin made for him to be buried in style.
Simon and his group of friends highly admire the Tamil superstar Vijay. However, their lives take an unexpected turn when their love for the actor makes them clash with two local criminals.
Chandran, a circus performer, and Thankam are in love. The circus team borrows some money from Thankam's father, Paithal Nair. When they are unable to repay, Paithal Nair takes away their animals.
A kind-hearted government employee in his forties, who spends most of his time with youngsters, selflessly intervenes in the problems of his near and dear ones.
Lekha Tharoor is an intelligent woman with a breadth of knowledge about everything who anchors a popular TV show of her own. She was blinded at a young age in an accident involving firecrackers. She gets her sight back after getting a transplant. However post the operation she starts getting strange visions which unfortunately makes the people around her think that she lost her mind.
Three cousins and their best friend leave for a road trip, hoping for one final hurrah before one of them gets married. Their path crosses with that of two girls who are on a getaway of their own. Their plans are derailed after a suspicious death. Who was the killer and why forms the plot.
Shekarankutty, a normal man with a wife and daughter, has trouble when his past as a mafia don is revealed.
Malick Bhai is a fish auctioneer, who is a familiar face in Cochin harbour. A foreigner girl Michelle enters his life. She comes to India with some motives and Malick Bhai decides to help her.