Sherlock Holmes has retired. But when MacDonald asks him to take on another case, he says yes. There have been some mysterious murders, and there are no visible causes for the deaths. At the same time Holmes gets this case, Graf Udo Von Felseck gives him another case: find a young and missing prince to prevent war between Germany and England. But Von Felseck is not as honest as he seems...
Sherlock Holmes and Dr. Watson are called in to unravel a mysterious curse that has plagued the Baskerville family for generations. When Sir Charles Baskerville is found dead, his heir, Sir Henry, begs Holmes to save him from the terrifying supernatural hound that has brought fear and death to his household.
When a nobleman is threatened by a family curse on his newly inherited estate, Sherlock Holmes is hired to investigate.
After spending decades living in the shadow of his more famous and successful sibling, Consulting Detective Sigerson Holmes (Wilder) is called upon to help solve a crucial case that leads him on a hilarious trail of false identities, stolen documents, secret codes... and exposed backsides.
Concerned about his friend's cocaine use, Dr. Watson tricks Sherlock Holmes into travelling to Vienna, where Holmes enters the care of Sigmund Freud. Freud attempts to solve the mysteries of Holmes' subconscious, while Holmes devotes himself to solving a mystery involving the kidnapping of Lola Deveraux.
Escaping from China with a microfilm of the formula for the mysterious "Lotus X", Lord Southmere, a Queen's Messenger, is chased by a group of Chinese spies.
After the death of his wife, wealthy retiree Justin Playfair creates a fantasy world for himself in which he is the legendary detective Sherlock Holmes, even dressing like the character. Out of concern for Justin's money more than his health, his brother Blevins puts him under the care of psychiatrist Dr. Mildred Watson. As Dr. Watson grows fond of Justin, she begins to play along with his theories, eventually becoming an assistant in his investigations.
A homicide detective teams up with an evolutionary biologist to hunt a giant creature that is killing people in a Chicago museum.
Sherlock Holmes and Watson are on the trail of a criminal and scientific mastermind who seems to control monsters and creations which defy belief.
Lupin squares off with two criminal families and Inspector Zenigata's new female patrol to track down a hoard of biblical-era treasure.
The Good Comrades are a collection of varied gentlemen who crave one thing - solitude. They reside at Drearcliff House, ancestral home of their eldest member. All seems serene and convivial until one by one the members begin to perish in the most grisly of manners. Foul play is suspected by the Good Comrades' insurance agent, who turns to Sherlock Holmes and Dr. John Watson for guidance.
The famous Borgia Pearl, a valuable gem with a history of bringing murder and misfortune to its owner since the days of the Borgias, is brought to London, thanks in part to Sherlock Holmes. But before long the jewel is stolen, due to an error on Holmes' part, and shortly thereafter, a series of horrible murders begin, the murderer leaving his victims with their spines snapped and surrounded by a mass of smashed china.
When a woman is found dead with her throat torn out, the local villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
The disappearance of people and corpses leads a reporter to a wax museum and a sinister sculptor.
After retrieving the Crystal Skull in Utah, Flynn Carsen receives a map in the mail with the secret location of King Solomon's Mines. When the scroll is stolen, Judson explains the power of the Key of Solomon's book and assigns Flynn to retrieve the map. The map is useless without the legend piece to decipher it, which is located in Volubilis near the Roman ruins in Morocco. Flynn heads to Casablanca to the ruins where he is chased by a group of mercenaries leaded by General Samir. They too want to find the location of King Solomon's mines. Flynn teams-up with Professor Emily Davenport working in the dig and they escape from General Samir and his men. While traveling to Gedi, they save the local Jomo from death and the trio faces a dangerous journey through the wild Africa.
Arthur Simon Simpson is a small-time crook biding his time in Greece. One of his potential victims turns out to be a gentleman thief planning to steal the emerald-encrusted dagger of the Mehmed II from Istanbul's Topkapi Museum.
Holmes and Dr. Watson take on the case of a beautiful woman whose husband has vanished. The investigation proves strange indeed, involving six missing midgets, villainous monks, a Scottish castle, the Loch Ness monster, and covert naval experiments.
The corpse of a shabbily dressed young woman has been discovered in the mud flats of the Thames at low tide. Police assume she's a prostitute, but Dr. Watson suspects something more and goes to his old friend Holmes, now retired and at very loose ends.
Sherlock Holmes and Dr. Watson meet as boys in an English Boarding school. Holmes is known for his deductive ability even as a youth, amazing his classmates with his abilities. When they discover a plot to murder a series of British business men by an Egyptian cult, they move to stop it.
When a nobleman is threatened by a family curse on his newly inherited estate, detective Sherlock Holmes is hired to investigate.