When David's sister returns home after a long absence, their complicated past comes back to haunt them.
Liz Lemon, the head writer for a late-night TV variety show in New York, tries to juggle all the egos around her while chasing her own dream.
Four ambitious and sexy women, who've been best friends since business school, try to balance their glamorous and demanding careers with their complex personal lives in the city that never sleeps. They've created their own "boys club" to protect each other and discuss their ups and downs as they try to have it all. What good is it to break the glass ceiling without girlfriends to share in your success?
Hope, a down-to-earth, happily married mother of three has her tidy world turned upside down when her celebrity sister moves in. Faith was living the Hollywood life as a soap opera star before her character was killed off.
In 1970s New York, jaded record exec Richie Finestra tries to resurrect his failing label and fractured personal life while keeping his finger on the pulse of the city's new sound.
The exploits of a group of men and women who serve the City of New York as police officers, firemen, and paramedics, all working the same fictional 55th precinct during the 3pm to 11pm shift - the 'Third Watch'.