The film opens with Bosko taking a bath while whistling "Singin' in the Bathtub". A series of gags allows him to play the shower spray like a harp, pull up his pants by tugging his hair, and give the limelight to the bathtub itself which stands on its hind feet to perform a dance.
Bosko is a construction worker who impresses Honey by making music from everything in sight, including a decapitated mouse, a typewriter and a goat filled with hot air.
Late at night, the mice come out and sing and play to the title tune, among others. That is, until the cat arrives, but he's quickly sent packing.
After failing to crush the bird with a boulder all by himself, Wile E. Coyote (Eternicus-failurus) attempts to catch Road Runner (Speedius-ludicrous) by using an ACME Clone-O-Matic.
Wile E. Coyote decides to use a freeze ray in order to catch Road Runner.
Wile E. Coyote (Fallious-flatius) uses an ACME Weather Control Kit to try and catch Road Runner (Speedius-gonzalicus) through various weather-related tricks.
It is Christmas in the Snake Bite Desert, and Road Runner is off on his usual sprint once again.
Among the strategies that fail in Wile E. Coyote's attempts to catch the Roadrunner: glue on the road, a giant rubber band, an outboard motor in a wash tub, and dressing in drag as a female Roadrunner.
A streetcar conductor, Foxy has adventures with a would-be passenger hippo, a cow blocking the tracks, and a runaway train while Foxy, his passengers, and some hobos sing the title song.
An old man is reading a book by the fire. The clock strikes 8, and he heads off to bed. From his book, Alice in Wonderland, out crawls Alice, who turns the radio to the title tune. This wakes up Rip Van Winkle; Alice then rouses the Three Musketeers, who sing a bit. Next tune: Nero fiddles, Rome burns, and Cleopatra sizzles in a slinky dance. Uncle Tom sings a spiritual as Mr. Hyde sneaks up and abducts Alice. Tarzan to the rescue, along with several other characters who mount a spirited attack using such office supplies as pen points, matches, and a fountain pen. They box him up and carry him off.
A bee returns home late after a night out having too much honey. His wife leaves him, but quickly ends up in the clutches of an evil large predator.
An American Indian boy and girl sing and dance in the forest along with the animals. Trouble begins when a fire threatens baby birds in their nest.
Honey is trying to teach the violin to Wilbur, the one who hates music. Honey calls Bosko over. Bosko and Honey sing, dance, and play music while Wilbur continues to express its disdain.
Bosko, Honey, and Bruno spend a day at the beach.
Bosko enters his dog, Bruno, in a dog race.
Bosko is a brave little boxer who battles the champion, Gas House Harry. The enormous brute proves a bit much, even for a plucky underdog. Some of the animation is later reused in "Bosko's Parlor Pranks" by M.G.M. in 1934.
While ice-skating on a frozen pond, Bosko and his dog discover a baby abandoned in the snow.
Bosko and Honey go to the zoo. Honey is frightened by the lion, but Bosko is the one who ends up in danger.
Bosko and his friends are cutting down trees in a forest. He battles a burly woodsman named Pierre who has gone off and kidnapped his beloved Honey.
Ride Him, Bosko! is a western-flavored cartoon with lots of shooting gags involving body reduction, and card characters singing! There's also an alcohol gag that has a really strong one turning a male piano player into a woman instantly!