Dan Evans, a small time farmer, is hired to escort Ben Wade, a dangerous outlaw, to Yuma. As Evans and Wade wait for the 3:10 train to Yuma, Wade's gang is racing to free him.
Vignettes weaving together the stories of six individuals in the old West at the end of the Civil War. Following the tales of a sharp-shooting songster, a wannabe bank robber, two weary traveling performers, a lone gold prospector, a woman traveling the West to an uncertain future, and a motley crew of strangers undertaking a carriage ride.
During the French Revolution, a surprising company shares a coach, trying to catch up something - the time itself, perhaps.
A scruffy garbage boy becomes the pupil of famed gunfighter Talby, and the stage for confrontation is set when the gunman overruns the boy's town through violence and corruption.
Bounty hunters seek shelter from a raging blizzard and get caught up in a plot of betrayal and deception.
A man tracks down the five outlaws who murdered his brother, all the while being shadowed by a mysterious Pinkerton detective.
After her stagecoach is ambushed, a woman is tasked with holding a dangerous outlaw captive and must survive the day when the bandit’s gang tries to free him.
Two Virginians are heading for a new life in Texas when they witness a stagecoach being held up. They decide to rob the robbers and make off with the loot. To escape a posse, they split up and don't see each other again for a long time. When they do meet up again, they find themselves on different sides of the law. This leads to the increasing estrangement of the two men, who once thought of themselves as brothers.
Spain, late 19th century. Judge Javier Zarco finds in a cemetery a skull pierced by a nail and suspects that a murder has been committed. When he investigates the case in depth, his suspicions fall on the woman who was going to marry the deceased.
A young lady named Hilda who works as a servant for the wealthy Clarksons, sheep farmers, and dreams of being a great singer. An upcoming visit by Sir Julian, a famous composer arriving from London, drives jealous Mrs. Clarkson (an interfering biddy who fancies she can sing - but can't) to send away Hilda, so he doesn't hear Hilda has a good voice. Meanwhile, an infamous outlaw named Stingaree has just arrived in town and kidnaps Sir Julian, then poses as him at the Clarksons, where he meets Hilda a few hours before she is to leave.
A band of outlaws, led by "Papa" Clellan, hold up in a ghost town as they plan an attack on a wagon train loaded with gold. The unexpected arrival of a stagecoach forces the gang to hold the passengers and driver as hostages. The later arrival of a wanderer, John Trey, sets in motion events not in "Papa" Clellan's original plan.
During the California Gold Rush, two down-on-their-luck vaudevillians attempt to become wealthy by bringing a girlie show to an all-male western mining town.
Stage line owner Brent has his men robbing Halliday stages and when his manager Waring learns of it, Brent has him killed. Jeff Waring arrives and takes his uncle's job. He soon learns what's happening and the Durango Kid goes into action. This keeps Halliday going and gives them a chance to get the mail contract by winning the stagecoach race.
John Russell, disdained by his "respectable" fellow stagecoach passengers because he was raised by Indians, becomes their only hope for survival when they are set upon by outlaws.
Lash and Fuzzy sent to help John Watson with his stage line arrive to find him murdered. Recognizing the outlaws they trail them to their leader Baxter. But before Baxter can tell who the big boss is he is shot. After getting the stage through to assure the mail contract, Lash now realizes who the boss is.
Ellen has the contract for the South West Stage Line through the panhandle. Her father had the run for years and Haney, who runs the office, worked for him. But Ellen does not know that Haney is in league with Elkins and they want the stage line so they can rob the gold shipments. All they need do is stop the stage and end her contract, but that is not easy with Dave driving for Ellen.
Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.
When Rocklin arrives in a western town he finds that the rancher who hired him as a foreman has been murdered. He is out to solve the murder and thwart the scheming to take the ranch from its rightful owner.
Gallant Cisco "kidnaps" murder suspect Ellen from the authorities, then sets about to prove her innocence, all with the cooperation of a sympathetic sheriff.
Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".