A Western-genre narrative, loosely woven from old clips from B-Western features.
A posse discovers a trio of men they suspect of murder and cow theft and are split between handing them over to the law or lynching them on the spot.
A female hustler is chasing after rich men, but becomes repeatedly mixed up with a suave con man and card shark through a series of misadventures before falling in love with him.
Opportunistic con man Dan Kehoe ingratiates himself with the cantankerous mother of four outlaws and their beautiful widows in order to find their hidden gold.
A wagon master and a con-man preacher help freed slaves dogged by cheap-labor agents out West.
Cheyenne Jones comes to the Blue River Ranch and asks for a job as a cowpuncher. Actually, Jones's real name is Buck McCloud and he's the new owner of the spread, having inherited it when his uncle died a year earlier. He's roaming the range incognito while trying to identify who's behind the cattle rustling that is afflicting his new business.
Quincy Drew and Jason O’Rourke, a pair of friends and con men—the former white, the latter a Northern-born free Black man— travel from town to town in the pre–Civil War American West. In their scam, Quincy sells Jason into slavery, frees him, and the two move on to the next town of suckers . . . until a con gone wrong leads Jason into real danger.
While on her way by stagecoach to visit relatives out west, Flower Belle Lee is held up by a masked bandit who also takes the coach's shipment of gold. When he abducts Flower Belle and they arrive in town, Flower Belle is suspected of being in collusion with the bandit.
A con artist arrives in a mining town controlled by two competing companies. Both companies think he's a famous gunfighter and try to hire him to drive the other out of town.
Notorious shootist and womanizer Quirt Evans' horse collapses as he passes a Quaker family's home. Quirt has been wounded, and the kindly family takes him in to nurse him back to health against the advice of others. The handsome Evans quickly attracts the affections of their beautiful daughter, Penelope. He develops an affection for the family and their faith, but his troubled past follows him.
Supernatural events on the range prompt an investigation by cowboy Brown in this western.
Sue Morgan gets Hoppy and his friends to join their expedition looking for Indian artifacts. Expedition leader Atwood makes a deal with nearby cattle rustler Morgan to loot the Indian treasures instead and sell them. Hoppy is on to their plan and pretending to leave follows them. Not only is he outnumbered by Morgan's men, but California has himself about to be sacrificed in an Indian ritual.
Before he was killed by Mark Foster's men, Bud Lawton willed part ownership in his ranch to Hoppy and his two pals. When the three arrive they find a fake posing as Lawton. When they expose the imposter, Foster gets the Sheriff to jail them for Lawton's murder.
Joe Weller has instigated a conflict over water rights between two ranchers. The idea is to have the ranchers do each other in then move in and take over. Hoppy and the good guys won't let this happen.
As rustled cattle have mysteriously disappeared, Johnny sends for his friend Hoppy, Hoppy arrives and immediately suspects Dan Slack. Realizing his telegram about Slack was intercepted, he locks up the operator Lafe knowing he can escape. Tailing Lafe he finds a secret entrance to a mine and inside finds the missing cattle. But Slack's men also find him just as the cattle are stampeded through the mine shaft.
Hoppy is busy chasing stagecoach bandits who sing as they rob.
Lee Garvin has eloped with the daughter of a railroad man who didn't approve of the marriage. Hoppy steps in when the young man is framed for murder.
European bad guy Baron Bendor leads some local townsmen in a plot to obtain horses through theft. Hoppy and his sidekicks Lucky and Speedy must find and expose the horse thieves.
Hopalong Cassidy and Johnny Nelson ride to the mountains to help a man and his daughter save their logging business from someone who is sabotaging their efforts.
When Ranger Hoppy's falsely accused young ranger friend is killed while supposedly trying to escape from jail, Hoppy is blamed and drummed out of the Texas Rangers.