Awkward teenager Charlie Bartlett has trouble fitting in at a new high school. Charlie needs some friends fast, and decides that the best way to find them is to appoint himself the resident psychiatrist. He becomes one of the most popular guys in school by doling out advice and, occasionally, medication, to the student body.
A young woman who has been in and out from rehab for the past 10 years returns home for the weekend for her sister's wedding.
January 1978. After their success in England, the punk rock band Sex Pistols venture out on their tour of the southern United States. Temperamental bassist Sid Vicious is forced by his band mates to travel without his troubled girlfriend, Nancy Spungen, who will meet him in New York. When the band breaks up and Sid begins his solo career in a hostile city, the turbulent couple definitely falls into the depths of drug addiction.
Hotshot real estate salesman Daryl has a bad cocaine habit. After embezzling his company's money, he wakes up next to a girl who overdosed. To hide from the police, he checks into a rehabilitation program guaranteeing anonymity. Under the mentorship of counselor Craig, Daryl accepts that he has a substance abuse problem. As he falls in love with fellow patient Charlie, Daryl begins committing to a newly sober life.
Gia Carangi meteorically rises to modeling fame in the late 1970s but becomes overconsumed by persistent loneliness and drug addiction.
Two childhood friends from South Boston turn to crime as a way to get by, ultimately causing a strain in their personal lives and their friendship.
Two best friends and recovering addicts embark on a frantic chase through New York City to stop the woman they are both in love with from killing her ex-boyfriend.
Rick (Rutger Hauer), a disaffected sailor turned hard drinking womanizer, returns home from six months at sea to find his wife (Corrigan), whom he was deeply in love, has unexpectedly left him and is now a junkie whore. Devastated, he tries to ease his pain with booze and cheap thrills. His wife's best friend (Dagmar Lassander) makes a move on him, and when he spurns her (after scewing her first, naturally) she plots her revenge. She does so in an ingenious way, by exploiting a fantasy woman of his, but her plan backfires with tragic consequences.
The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.
A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.
The brief life of Jean Michel Basquiat, a world renowned New York street artist struggling with fame, drugs and his identity.
Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide to travel cross-country in search of spiritual truth.
Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.
A dramatic history of Pu Yi, the last of the Emperors of China, from his lofty birth and brief reign in the Forbidden City, the object of worship by half a billion people; through his abdication, his decline and dissolute lifestyle; his exploitation by the invading Japanese, and finally to his obscure existence as just another peasant worker in the People's Republic.
People in the future live in a totalitarian society. A technician named THX 1138 lives a mundane life between work and taking a controlled consumption of drugs that the government uses to make puppets out of people. As THX is without drugs for the first time he has feelings for a woman and they start a secret relationship.
Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.
In late 1960s New York City, fed up with monotonous college life and police repression, free-spirited Fritz, an impenitent seducer and unrestrained party-animal, decides to explore the world. And just like that, as he flees NYC, heading to San Francisco, Fritz embarks on an endless adventure of illumination. Immersed in a world surrounded by drugs and sex, Fritz participates in mad orgies, brings about a revolution, incites mass urban riots, and crosses paths with drug-addled Nazi bikers.
In the mid-1960s, wealthy debutant Edie Sedgwick meets artist Andy Warhol. She joins Warhol's famous Factory and becomes his muse. Although she seems to have it all, Edie cannot have the love she craves from Andy, and she has an affair with a charismatic musician, who pushes her to seek independence from the artist and the milieu.
While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.
After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.