A medical school dropout loses his fiancée in a tragic lawnmower incident and decides to bring her back to life. Unfortunately, he was only able to save her head, so he goes to the red light district in the city and lures prostitutes into a hotel room so he can collect body parts to reassemble her.
Dr. Laurence, a once-respectable scientist, begins to research the origin of the mind and the soul. The science community rejects him, and he risks losing everything for which he has worked. He begins to use his discoveries to save his research and further his own causes, thereby becoming... a Mad Scientist, almost unstoppable...
A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
Upon arriving at the dilapidated estate of his mentor, Dr. Harker finds his former professor, Dr. Usher, radically changed. Instead of the reasoned scholar he once knew, a paranoid man is in his place and he's spiraling into madness.
In foggy London Dr Jekyll experiments on newly deceased women determined to discover an elixir for immortal life. Success enables his spectacular transformation into the beautiful but psychotic Sister Hyde who stalks the dark alleys of Whitechapel for young, innocent, female victims, ensuring continuation of the bloodstained research. With each transformation Sister Hyde becomes the more dominant personality, determined to eventually suppress the frail, ineffectual Dr Jekyll forever.
A mad scientist (Donald Pleasence) crosses plants with people, and the results wind up in a sideshow.
After a wave of reports of mysterious attacks involving people and pets being eaten by the traditionally docile fruit, a special government task force is set up to investigate the violent fruit and put a stop to their murderous spree.
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.
A scientist keeps his wife young by killing, stealing the bodies of, and taking the gland fluid from virgin brides.
A physician on death row for a mercy killing is allowed to experiment on a serum using a criminals' blood, but secretly tests it on himself. He gets a pardon, but finds out he's become a Jekyll-&-Hyde.
Dr. Leon Kravaal develops a potential cure for cancer, which involves freezing the patient. But an experiment goes awry when authorities believe Kravaal has killed a patient. Kravaal freezes the officials, along with himself. Years later, they are discovered and revived in hopes that Kravaal can indeed complete his cure. But human greed and weakness compound to disrupt the project.
Dr. Henryk Savaard is a scientist working on experiments to restore life to the dead. When he is unjustly hanged for murder, he is brought back to life by his trusted assistant. Re-animated he turns decidedly nasty and sets about murdering the jury that convicted him.
Working in Dr. Cranley's laboratory, scientist Jack Griffin was always given the latitude to conduct some of his own experiments. His sudden departure, however, has Cranley's daughter Flora worried about him. Griffin has taken a room at the nearby Lion's Head Inn, hoping to reverse an experiment he conducted on himself that made him invisible. But the experimental drug has also warped his mind, making him aggressive and dangerous. He's prepared to do whatever it takes to restore his appearance.
Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.
Four explorers are summoned to Peru by the brilliant physicist Dr Thorkel. They discover a rich source of radium and a half-mad Thorkel who shrinks them down to one-fifth their normal size when they threaten to stop his unorthodox experimentation.
Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
Deranged scientist, Gustav Niemann, escapes from prison and overtakes the director of a traveling chamber of horrors, soon reviving the infamous Count Dracula, the frozen Frankenstein Monster, and the Wolf Man.