Three brothers stop off for a night in the town of Tombstone. The next morning they find one of their brothers dead and their cattle stolen. They decide to take revenge on the culprits.
In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.
Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.
Legendary marshal Wyatt Earp, now a weary gunfighter, joins his brothers Morgan and Virgil to pursue their collective fortune in the thriving mining town of Tombstone. But Earp is forced to don a badge again and get help from his notorious pal Doc Holliday when a gang of renegade brigands and rustlers begins terrorizing the town.
From Wichita to Dodge City, to the O.K. Corral in Tombstone, Wyatt Earp is taught that nothing matters more than family and the law. Joined by his brothers and Doc Holliday, Earp wages war on the dreaded Clanton and McLaury gangs.
Dan Evans, a small time farmer, is hired to escort Ben Wade, a dangerous outlaw, to Yuma. As Evans and Wade wait for the 3:10 train to Yuma, Wade's gang is racing to free him.
Two investigators for a stagecoach company are assigned to find out why the company's stages keep being ambushed. They discover that the culprits are white men disguised as Indians, and they set out to discover who is behind the plot.
Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".
A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.
The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.
A Confederate troop, led by Captain Lafe Barstow, is prowling the far ranges of California and Nevada in a last desperate attempt to build up an army in the West for the faltering Confederacy. Because the patrol saves a stagecoach, with Johanna Carterr as one of the passengers, from an Indian attack, and is marooned on a rocky mountain, it fails in its mission but the honor of the Old South is upheld.
In 1865, a troop of Confederate soldiers led by Major Matt Stewart attack the wagon of gold escorted by Union cavalry and the soldiers are killed. The only wounded survivor tells that the war ended one month ago, and the group decides to take the gold and meet their liaison that knew that the war ended but did not inform the troop. The harsh Rolph Bainter kills the greedy man and the soldiers flee in his wagon driven by Major Stewart. When they meet a posse chasing them, Stewart gives wrong information to misguide the group; however, they have an accident with the wagon and lose the horses. They decide to stop a stagecoach and force the driver to transport them, but the posse returns and they are trapped in the station with the passenger. They realize that the men are not deputies and have no intention to bring them to justice but take the stolen gold.
John Russell, disdained by his "respectable" fellow stagecoach passengers because he was raised by Indians, becomes their only hope for survival when they are set upon by outlaws.
Jim Bannon and his partner own a stagecoach line. With the coming of the telegraph and the end of the Pony Express, two men plot to take over and get the new mail contract. When Jim's partner is murdered and Jim's name is written in the sand beside the body, Jim is arrested. At his trial Whip brings surprising evidence that clears Jim and the two plotters are soon arrested.
The Trail Blazers are bringing in a prisoner to stand trial for bank robbery, when several attempts are made to kill him; convinced of the man's innocence, they arrange a trap for the real thieves.
As prisoner Ed Archer is being transferred, the stage is attacked and crashes. Archer escapes the attackers but Ranger Rocky Lane catches up with him. As Rocky is bringing him in, Archer is attacked again. Somebody wants Archer killed and Rocky, now suspecting Archer is innocent, decides to find out who and why.
An independent former ranch foreman and an heiress are kidnapped by a trio of ruthless outlaws.
After a stagecoach holdup, Frank Slayton's notorious gang leave Ben Warren for dead and head off with his fiancée. Warren follows, and although none of the townspeople he comes across are prepared to help, he recruits two others who have sworn revenge on the ruthless Slayton.