Sherlock Holmes and Watson are on the trail of a criminal and scientific mastermind who seems to control monsters and creations which defy belief.
The Good Comrades are a collection of varied gentlemen who crave one thing - solitude. They reside at Drearcliff House, ancestral home of their eldest member. All seems serene and convivial until one by one the members begin to perish in the most grisly of manners. Foul play is suspected by the Good Comrades' insurance agent, who turns to Sherlock Holmes and Dr. John Watson for guidance.
The famous Borgia Pearl, a valuable gem with a history of bringing murder and misfortune to its owner since the days of the Borgias, is brought to London, thanks in part to Sherlock Holmes. But before long the jewel is stolen, due to an error on Holmes' part, and shortly thereafter, a series of horrible murders begin, the murderer leaving his victims with their spines snapped and surrounded by a mass of smashed china.
When a woman is found dead with her throat torn out, the local villagers blame a supernatural monster. But Sherlock Holmes, who gets drawn into the case from nearby Quebec, suspects a human murderer.
Sherlock Holmes investigates when young women around London turn up murdered, each with a finger severed. Scotland Yard suspects a madman, but Holmes believes the killings to be part of a diabolical plot.
Sherlock Holmes is drawn into the case of Jack the Ripper, who is killing prostitutes in London's East End. Assisted by Dr. Watson, and using information provided by a renowned psychic, Robert Lees, Holmes finds that the murders may have their roots in a Royal indiscretion and that a cover-up is being managed by politicians at the highest level, all of whom happen to be Masons.
Sherlock Holmes and Dr. Watson embark on a search for Cleopatra's ancient necklace, which has been stolen.
Early in his crime-solving career, Sherlock Holmes attempts to prevent Moriarty from cornering the heroin market.
In London, a secret society led by lawyer Thaddeus Merrydew collects the assets of any of its deceased members and divides them among the remaining members. Society members start dropping like flies. Sherlock Holmes is approached by member James Murphy's widow, who is miffed at being left penniless by her husband. When Captain Pyke is shot, Holmes keys in on his mysterious Chinese widow as well as the shady Merrydew. Other members keep dying: Malcom Dearing first, then Mr. Baker. There is also an attempt on the life of young Eileen Forrester, who became a reluctant society member upon the death of her father. Holmes' uncanny observations and insights are put to the test.
Based on the feature-length novel "The Hound of the Baskervilles" written by Arthur Conan Doyle, which is the movie version of the TV drama "Sherlock" broadcast on the Fuji TV series in 2019.
Holmes, retired to Sussex, is drawn into a last case when his arch enemy Moriarty arranges with an American gang to kill one John Douglas, a country gentleman with a mysterious past. Holmes' methods baffle Watson and Lestrade, but his results astonish them. In a long flashback, the victim's wife tells the story of the sinister Vermissa Valley.
After her sister dies under mysterious circumstances, a young heiress seeks Holmes' help when she feels threatened by her brutish stepfather.
After the King of Rovenia has been assassinated, Holmes and Watson are engaged to escort his son to Europe via Algiers, aboard a transatlantic ocean liner which also carries a number of suspicious persons, any of whom may be involved in a plot to also assassinate him.
During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.
In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.
Holmes receives a mysterious telegram from Cyril Overton, the captain of the Cambridge University rugby team. Overton later explains that one of the best players on his team, a young man named Godfrey Staunton, went missing while in London for an important game. Holmes follows a trail of clues back to Cambridge.
Hilton Soames, a lecturer in Greek at a university, notices that someone has gone into his study and looked at the text for an unseen translation exam that is due to take place the next day. Suspicion falls on the three students who live in the same building in which Soames lives and works, all of whom are entered for the exam.
Sherlock Holmes is a master at solving the most impenetrable mysteries, but he has his work cut out for him on his latest case. As the famed detective investigates an alleged theft, he’s brought face to face with his most devious adversary yet — Professor Moriarty.
Holmes takes a vacation and visits his old friend Sir Henry Baskerville. His vacation ends when he suddenly finds himself in the middle of a double-murder mystery. Now he's got to find Professor Moriarty and the horse Silver Blaze before the great cup final horse race.
While searching for her missing mother, intrepid teen Enola Holmes uses her sleuthing skills to outsmart big brother Sherlock and help a runaway lord.