The music-happy Bosko and Honey take a car ride, but bad luck briefly interrupts their fun.
Bosko is a construction worker who impresses Honey by making music from everything in sight, including a decapitated mouse, a typewriter and a goat filled with hot air.
Wile E. Coyote tries to outsmart Road Runner with his painting skills.
Late at night, the mice come out and sing and play to the title tune, among others. That is, until the cat arrives, but he's quickly sent packing.
Among the strategies that fail in Wile E. Coyote's attempts to catch the Roadrunner: glue on the road, a giant rubber band, an outboard motor in a wash tub, and dressing in drag as a female Roadrunner.
Bosko has a grand time on the farm, dancing with a cow, playing a horse's tail like a violin and getting drunk with three pigs.
Bosko hunts in the jungle, but ends up playing music with the animals.
Bosko and his porcine friend are hobos in a runaway boxcar.
Bosko, Honey, and Bruno spend a day at the beach.
Bosko enters his dog, Bruno, in a dog race.
While ice-skating on a frozen pond, Bosko and his dog discover a baby abandoned in the snow.
Honey is trying to teach the violin to Wilbur, the one who hates music. Honey calls Bosko over. Bosko and Honey sing, dance, and play music while Wilbur continues to express its disdain.
While romping through the forest, Bosko falls asleep and dreams of giants and gnomes.
Bosko and his friends are cutting down trees in a forest. He battles a burly woodsman named Pierre who has gone off and kidnapped his beloved Honey.
Ride Him, Bosko! is a western-flavored cartoon with lots of shooting gags involving body reduction, and card characters singing! There's also an alcohol gag that has a really strong one turning a male piano player into a woman instantly!
An expectant father rooster fetches doctor stork, who comes out with a basket full of white chicks and one little black one, who gets crowded out of the food. After singing the title song, he manages to improvise a pair of wings and fly over the chicken coop, but regrets it when he is chased by a mean scarecrow.
On a tropical island, a native boy sings "Pagan Moon" to his sweetheart. Later, he plays music underwater with an octopus-pianist and other jazz-loving sea life.
Bosko is the star player in a wacky game of professional football.
Bosko and Bruno escape from a speeding train via a handcar; make a failed attempt to steal a chicken; and end up on a runaway boxcar.
A mannequin in the city dump improvises a working piano from junk, then plays and sings the title song. Various discarded items join in with song or dance.