Jim Crosby, the product of a broken home, becomes a gangster and goes to prison. Meanwhile, Ann Payton, an heiress, converts a saloon into a mission. She is engaged to her father's secretary, Temple Vaughn, a gambler. Jim is released from prison and seeks shelter at the mission. Temple becomes indebted to gambler Phil Johnson and is forced to arrange a crooked poker game involving some of his wealthy friends. Jim overhears the plot and, realizing that Temple is Ann's fiancé, robs the poker game and puts a check Temple forged into Temple's own pocket.
Bessie Allen, a girl of the slums, dances in the streets of the Lower East Side of New York to the delight of the crowds. She becomes an orphan when her father, in a drunken stupor, kills her mother, and then himself. Bessie is knocked down by the car of Mrs. Latham, a society matron, who takes an interest in the girl and procures her a job as a dress model.
George Bell, a wild young man, lives with his rancher father, Thomas Bell, in Paradise Valley, California. When George sells his father's favorite horse, Mr. Bell turns him out, and George becomes a grain salesman in St. Louis. Meanwhile, Polly Martin lives with her father Bill, an ex-businessman who has sunk to day-labor because of his addiction to alcohol. Bill frequently abuses Polly, and when he falls to his death from a high girder, Polly becomes a nurse in the Salvation Army in St. Louis. George falls in love with Polly after he saves her from the advances of a drunk, but she will not marry him because of his wild past.
In 1869, enemies of railroad magnate Richard Strong attempt to ruin him. Richard thwarts them, largely through the help of Charles Dalton, but then Charles tries to seduce Elinor, Richard's wife. Although she rebuffs Charles, Richard accuses her of infidelity, so Elinor leaves him and goes to Paris. Richard follows her, but, caught in the middle of the 1870 riots, he cannot get near her. Charles, also in Paris, finally convinces Richard that nothing had come of his interest in Elinor, but Richard now believes that Elinor no longer loves him.
When penniless Westie Phillips briefly meets wealthy Martha Gorham, he falls in love, but Martha forgets the encounter. Harry Arnold, courting Martha, invites her out sailing and arranges to have the yacht wrecked near an uncharted island so that he can be alone with her until rescuers arrive. Meanwhile, without knowing Martha is on board, Westie secures a position on the yacht.
Although Kenneth Carmont and Esther Saunders, criminal Bert Saunders' sister, love each other, Esther marries detective Elwood Collins, who agrees to stop pursuing Bert if she accepts his proposal. One night, Kenneth and Esther hide Bert, who has escaped from the police. The same night, Kenneth's father is murdered. The evidence implicates Kenneth, who cannot supply his whereabouts at the time of the crime, as that would give away Bert. Esther cannot clear Kenneth for the same reason, and because it would let her husband know that she was with her former sweetheart.
Finding himself penniless, Lawrence Ashmore, whose late father was ruined on the stock exchange, obtains a position as a reporter. Ashmore is assigned to investigate the reported fatal illness of Jesse Craven, one of Wall Street's financial monarchs.
For Nita Valyez, who is half-Spanish and half-Irish, Carlos represents potential violence and danger, two things to which she is both attracted and repelled. In contrast, she has only a passing interest in Big Jim, the town's honest, good-hearted sheriff. Then, after Carlos kills a faro dealer, he forces Nita to make an escape with him.
When New York playwright Richard Warrington returns to his home town, Republican bosses nominate him for mayor. The Democrats, alarmed at Richard's popularity, decide to unearth a scandal that will ruin his chances of winning and quickly discover that, months before, actress Katherine Challoner had spent the night in Richard's apartment. Although it simply had been the result of Katherine's fainting spell, the home-town Democratic newspaper turns the overnight visit into an illicit rendezvous between two lovers.
Montgomery Seaton, one of the idle rich, pays more attention to his friends' business than to his marital situation.
In their small village, Romanian peasant girl Katinka Veche falls in love with the studious Jan Drakachu. Jan wins a scholarship to an American university eventually becoming a successful engineer. Unbeknownst to him, Katinka, whom he had to leave behind in the village, is sold into slavery by her cruel, dissolute father. Her owner, Victor Dravich, beats her into submission forcing her to become his mistress in his Syrian gambling den. When the house is raided, Dravich takes her on his travels around the world until they finally settle in a small Arizona mining camp. Broken, she sees Jan but is too ashamed to speak to him sending instead for her old tutor Boris. Upon arrival Boris kills Dravich but is shot by the sheriff. Katinka, now free, follows Jan to New York. After further travail the pair are finally reunited.
Mr. Williams, a stern father and man of wealth, disinherits his son Hugh, for marrying Rose, a seamstress. Twenty years later, although Sose is practically supporting her sick husband, their little store is taken from them and they are obliged to move, with Martha, their daughter, to the tenement district.
Saved from a terrible shipwreck by Stephan Royston, son of a farmer. Nana, orphaned by the catastrophe, is adopted by the family and the two sons, Stephan and Godfrey, fall in love with her. Stephan's artistic tendency for painting, etc., is classed as foolishness by his stern father, while Godfrey, realizing that the girl favors his brother, determines to get rid of him.
Dale Aldis and John Coventry, who were sweethearts as children, meet again after the death of Dale's mother and discover that they are still in love.
According to Richard Standhope's will, both his daughter Laura and her long-lost twin brother Larry must be reunited by a certain date, or the estate will revert to her avaricious guardian, Andrew Brean. Following Standhope's death, Laura and her sweetheart, Jim Watson, read in her deceased mother's diary that Andrew had broken up the Standhopes' marriage soon after the twins' birth by unjustly accusing Mrs. Standhope of infidelity. Laura was then sent to boarding school, while little Larry, placed in his father's care, was neglected and later became a thief. As Laura and Jim ponder Larry's whereabouts, the house is robbed by none other than Larry, now called "the Kid," and his cohort, "the Snail."
U.S. Navy Lieutenant George Blenton becomes drunk at an official reception, and his fiancee, Jane Ravenslee, the captain's daughter, breaks their engagement. After war is declared, George, entrusted with a secret code book to deliver to an English admiral, drinks and loses the book which German spies recover. During a private court-martial he is offered a pistol for suicide. After drinking again, he fires a shot, but still lives. Put ashore on the island of Tafofu "to rot," George, hating the U.S., moves in with Lehua, a half-white who tries to wean him from drink.
Hugon, a Canadian backwoodsman who is respected for his strength both of limb and of character, falls in love with Marie even though she has another sweetheart, a young man named Gabriel. Realizing that Marie favors Gabriel, Hugon good-naturedly offers to help the boy develop muscles and stamina but soon abandons the hopeless task. Meanwhile, Roque and his group of crooked surveyors have made plans to swindle the woodsman out of his property.
Roma Wycliffe, a high-spirited girl bored with the lavender-and-old-lace atmosphere of her Aunt Henrietta's estate, discovers that her grandmother was a gypsy and decides to become one herself.
Muggsy Mulane, a waif who wears boy's clothing, jumps a freight train to the country after Jimmy "the Eel," the leader of the gang of crooks with whom she works, is arrested. In the village of Cottonville, Muggsy befriends Aunt Sarah, whom she later discovers is Jimmy's mother. When Muggsy learns that the greedy Judge Cotton, who holds the mortgage on Aunt Sarah's property, is planning to foreclose, she threatens to blackmail him, and he relents.
Mr Bernhard has financial difficulties. He has fallen into the hands of broker Mr Pouzer. In desperation, Bernhard's daughter Julia visit Pouzer to ask for mercy for her father. Yes, Pouzer replies, if I get you in return.